501939-52-2Relevant academic research and scientific papers
ISOXAZOLINE HYDROXAMIC ACID DERIVATIVES AS LPXC INHIBITORS
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Page/Page column 76, (2015/11/10)
This invention pertains generally to compounds of Formula I and compositions containing such compounds, as well as methods of using such compounds to treat bacterial infections. In certain aspects, the invention pertains to methods and compositions for tr
Regioselective synthesis of 2,6-dimethyl-3,5-bis[(3-aryl-5-trifluoromethyl) -isoxazol-4-carbonyl]-pyridine derivatives
Yang, Yindi,Zhang, Min,Zhu, Yiwen,Zhang, Li,Xie, Qiqiang,Song, Liping,Deng, Hongmei
, p. 950 - 954 (2013/08/23)
Ethyl 4,4,4-trifluoro-3-oxo-butyrate reacted with 2,6-dimethyl-3,5- diacetyl-pyridine 1 in the presence of NaOC2H5 at 0°C to give 2,6-dimethyl-3,5-bis(4,4,4-trifluoro-1,3-oxo-butyl)-pyridine (2a) in good yield. Cyclization reaction o
ANTIMICROBIAL INDOLINE COMPOUNDS FOR TREATMENT OF BACTERIAL INFECTIONS
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Page/Page column 35, (2010/04/23)
The present invention provides indoline heterocyclic compounds of the following formula I: or pharmaceutically acceptable salts, prodrugs, solvates, or hydrates thereof useful as antibacterial agents, pharmaceutical compositions containing them, methods f
