501953-23-7

Upstream product

• 30494-32-7 3-chlorocyclobutane carboxylic acid chloride 
• 40400-13-3 2-Iodobenzyl bromide 

Downstream Products

• 705297-46-7 1-(3-chloro-cyclobutyl)-2-(2-iodo-phenyl)-ethanol 
• 705297-05-8 1-[2-(trans-3-chlorocyclobutyl)allyl]-2-iodobenzene 
• 501953-42-0 1-(2-cyclobut-2-enylallyl)-2-iodobenzene 
• 705297-04-7 2-(2-iodobenzyl)-1-(cis-3-phenylselanylcyclobutyl)ethanol 
• 705297-10-5 1-[2-(cis-3-phenylselanylcyclobutyl)allyl]-2-iodobenzene 
• 501953-37-3 2-(2-iodobenzyl)-2-(cis-3-phenylselenylcyclobutyl)-[1,3]-dioxolane 
• 501953-30-6 2-cyclobut-2-enyl-2-(2-iodobenzyl)-[1,3]-dioxolane 
• 501953-25-9 2-(trans-3-chlorocyclobutyl)-2-(2-iodobenzyl)-[1,3]-dioxolane 

Relevant academic research and scientific papers

Radical and palladium-catalyzed cyclizations to cyclobutenes: An entry to the BCD ring system of penitrem D

A novel approach toward the synthesis of the BCD ring system of penitrem D is described. The strategy capitalizes on the fast cyclization rates of aryl radicals into cyclobutenes and allows access to a variety of fused tricyclic structures. Radical/polar

Samarium(II) iodide mediated radical/polar crossover reactions of cyclobutenes. An efficient approach to the BCD ring system of the penitrems.

[reaction: see text] Radical/polar crossover reactions of derivatives of 1-(2-cyclobutenyl)-2-(2-iodoaryl)ethanones with acetone promoted by samarium diiodide and HMPA provide 1-(1-hydroxy-1-methylethyl)-2,2a,4,8b-tetrahydro-1H-cyclobuta[a]naphthalen-3-on