502160-52-3

Upstream product

• 619-42-1 4-methoxycarbonylphenyl bromide 
• 502160-49-8 methyl 4-[2-(2-pivaloylamino-4-vinyl-6-methylpyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate 
• 502160-50-1 methyl 4-[2-(2-pivaloylamino-4-ethyl-6-methylpyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate 
• 502160-48-7 methyl 4-[2-(2-pivaloylamino-4-chloro-6-methylpyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoate 
• 502160-51-2 4-[2-(2-amino-4-ethyl-6-methylpyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoic acid 
• 176208-13-2 methyl 4-<2-(2-amino-6-methyl-4(3H)-oxo-7H-pyrrolo<2,3-d>pyrimidin-5-yl)ethyl>benzoate 
• 103094-70-8 methyl 4-(4-oxopentyl)benzoate 
• 111957-98-3 Pent-4-en-2-ol 
• 1118-89-4 diethyl-L-glutamate hydrochloride 

Relevant academic research and scientific papers

Design, synthesis, and biological activities of classical N-{4-[2-(2-amino-4-ethylpyrrolo[2,3-d]pyrimidin-5-yl)ethyl] benzoyl}-L-glutamic acid and its 6-methyl derivative as potential dual inhibitors of thymidylate synthase and dihydrofolate reductase and

Two novel analogues, N-{2-amino-4-ethyl[(pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl}-L-glutamic acid (2) and N-{2-amino-4-ethyl-6-methyl[(pyrrolo[2,3-d]pyrimidin-5-yl) ethyl]benzoyl}-L-glutamic acid (4), were designed and synthesized as potent dual inhibi