502176-97-8

Upstream product

• 591-50-4 iodobenzene 
• 502176-89-8 6-(tert-butyldimethylsiloxy)-1,7-nonadiyn-9-ol 
• 502176-91-2 6-(tert-butyldimethylsiloxy)-1-phenyl-1,7-nonadiyn-9-ol 
• 502176-87-6 6-(tert-butyldimethylsiloxy)-1-(trimethylsilyl)-1,7-nonadiyn-9-ol 
• 943733-94-6 8-(trimethylsilyl)octa-1,7-diyn-3-ol 
• 928-90-5 5-hexyl-1-ol 
• 502176-85-4 6-(tert-butyldimethylsiloxy)-1-(trimethylsilyl)-1,7-octadiyne 
• 117948-96-6 6-(trimethylsilyl)-5-hexynal 
• 103437-52-1 6-trimethylsilanyl-hex-5-yn-1-ol 

Downstream Products

• 502177-03-9 9-phenyl-3-(phenylsulfonyl)-1,2-nonadien-8-yn-4-ol 

Relevant academic research and scientific papers

Efficient construction of the bicyclo[5.3.0]decenone skeleton based on the Rh(I)-catalyzed allenic Pauson-Khand reaction

A reliable procedure for constructing a bicyclo[5.3.0]deca-1,7-dien-9-one ring system by rhodium-catalyzed Pauson-Khand reaction (PKR) of allenynes with a sulfonyl group has been developed. Investigation of the rhodium-catalyzed PKR on 19 examples of 1,2-nonadien-8-yne derivatives demonstrated that (i) acceptable yields could be consistently achieved through the proper choice of the rhodium catalyst ([RhCl(CO)2]2 or [RhCl(CO)dppp]2) depending on the starting allenyne and that (ii) an ester functionality as well as hydroxy and siloxy groups could be tolerated in this rhodium-catalyzed PKR.