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4-Methoxycanthin-6-one is a naturally occurring chemical compound found in certain plants, particularly in the Senna species. It is a yellow crystalline substance with a molecular formula of C10H7NO3 and a molecular weight of 191.17 g/mol. 4-METHOXYCANTHIN-6-ONE is structurally related to canthin-6-one, a known alkaloid with potential biological activities. 4-Methoxycanthin-6-one has been studied for its potential pharmacological properties, including its ability to act as a dopamine reuptake inhibitor, which may have implications for the treatment of neurological disorders. However, further research is needed to fully understand its therapeutic potential and safety profile.

5023-08-5

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5023-08-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5023-08-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,0,2 and 3 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 5023-08:
(6*5)+(5*0)+(4*2)+(3*3)+(2*0)+(1*8)=55
55 % 10 = 5
So 5023-08-5 is a valid CAS Registry Number.

5023-08-5Downstream Products

5023-08-5Relevant academic research and scientific papers

Total synthesis of cordatanine, structural reassignment of drymaritin, and anti-inflammatory activity of synthetic precursor

Fang, Hsin Wei,Liao, Yu-Ren,Hwang, Tsong-Long,Shieh, Po-Chuen,Lee, Kuo-Hsiung,Hung, Hsin-Yi,Wu, Tian-Shung

, p. 3822 - 3824 (2015)

Abstract In this study, cordatanine, with a canthin-6-one skeleton, was totally synthesized in four steps via a Pictet-Spengler reaction using tryptamine and methyl glyoxylate with a total yield of 8%. The NMR spectra of synthesized cordatanine compared well with those of drymaritin isolated by Hsieh et al., confirming the need to revise the original structural assignment. In addition, kumujian A, a synthetic intermediate, showed significant anti-inflammatory effects, inhibiting both superoxide anion generation (IC50 4.87 μg/mL) and elastase release (IC50 6.29 μg/mL).

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