502495-32-1

Basic information

• Product Name: {(S)-3-[1-Bromo-meth-(Z)-ylidene]-4-methylene-cyclohexyloxy}-tert-butyl-dimethyl-silane
• Synonyms: {(S)-3-[1-Bromo-meth-(Z)-ylidene]-4-methylene-cyclohexyloxy}-tert-butyl-dimethyl-silane
• CAS NO: 502495-32-1
• Molecular Weight: 317.341
• Mol File: 502495-32-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(S)-3-[1-Bromo-meth-(Z)-ylidene]-4-methylene-cyclohexyloxy}-tert-butyl-dimethyl-silane(CAS DataBase Reference)
• NIST Chemistry Reference: {(S)-3-[1-Bromo-meth-(Z)-ylidene]-4-methylene-cyclohexyloxy}-tert-butyl-dimethyl-silane(502495-32-1)
• EPA Substance Registry System: {(S)-3-[1-Bromo-meth-(Z)-ylidene]-4-methylene-cyclohexyloxy}-tert-butyl-dimethyl-silane(502495-32-1)

Safety Data

• Hazardous Substances Data: 502495-32-1(Hazardous Substances Data)

Upstream product

• 502495-31-0 (S)-1-Trimethylsilanyl-oct-7-en-1-yn-4-ol 
• 143724-89-4 Trimethyl-((R)-3-oxiranyl-prop-1-ynyl)-silane 

Downstream Products

• 67-97-0 vitamin D₃ 
• 87649-56-7 tert-Butyl-{(S)-3-[2-[(1R,3aS,7aR)-1-((R)-1,5-dimethyl-hexyl)-7a-methyl-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-4-methylene-cyclohexyloxy}-dimethyl-silane 

Relevant articles and documents

Efficient convergent synthesis of 1alpha,25-dihydroxyvitamin D3 and its analogues by Suzuki-Miyaura coupling.

[reaction: see text] 1alpha,25-Dihydroxyvitamin D(3) was synthesized by the Suzuki-Miyaura coupling of the A-ring intermediate 1, which was efficiently prepared from readily available 1,7-enyne 2, with the corresponding boronate compound of the C,D-ring portion. The method was applied to prepare des-C,D analogues of 1alpha,25-dihydroxyvitamin D(3).