502496-22-2

Usage

Uses

Used in Pharmaceutical Industry:
(4-FLUORO-3-TRIFLUOROMETHYL-PHENYL)-HYDRAZINE HYDROCHLORIDE is used as a chemical intermediate for the synthesis of various pharmaceutical compounds due to its unique structural features that can be leveraged to create new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical field, (4-FLUORO-3-TRIFLUOROMETHYL-PHENYL)-HYDRAZINE HYDROCHLORIDE is utilized as a building block in the development of novel agrochemicals, potentially enhancing crop protection and yield through its incorporation into pesticides or other agricultural chemicals.
Used in Material Science:
(4-FLUORO-3-TRIFLUOROMETHYL-PHENYL)-HYDRAZINE HYDROCHLORIDE is employed as a component in the advancement of new materials with specialized properties. Its unique molecular structure may contribute to the creation of materials with improved characteristics for various applications in science and engineering.
Used in Research and Development:
As a compound with potential biological activities, (4-FLUORO-3-TRIFLUOROMETHYL-PHENYL)-HYDRAZINE HYDROCHLORIDE is used in research for exploring its interactions with biological systems, which can lead to a better understanding of its mechanisms of action and potential applications in medicine and other fields.

InChI:InChI=1/C7H6F4N2.ClH/c8-6-2-1-4(13-12)3-5(6)7(9,10)11;/h1-3,13H,12H2;1H

Upstream product

• 2357-47-3 4-Fluoro-3-trifluoromethylaniline 

Downstream Products

• 1257339-27-7 1-(4-fluoro-3-trifluoromethylphenyl)-1H-pyrazol-3-ol 
• 1257339-13-1 3-(2-((1-(4-fluoro-3-(trifluoromethyl)phenyl)-2H-pyrazol-3-yloxy)methyl)phenyl)oxazolidin-2-one 
• 1263406-28-5 C₁₀H₈F₄N₂O 

Relevant academic research and scientific papers

Synthesis, fungicidal activity, structure-activity relationship and density functional theory studies of novel oxime ether derivatives containing 1-aryl-3-oxypyrazoles

A series of 16 oxime ether derivatives containing 1-aryl-3-oxypyrazoles were synthesised, and the structure of one of them, (E)-methyl 2-(2-({(1-(4-chlorophenyl)-1H-pyrazol-3-yl)-oxy}methyl)phenyl)-2-(methoxyimino)acetate was determined by X-ray diffraction crystallography. Preliminary bioassays indicated that some of these compounds exhibited very good fungicidal activities against Rhizoctonia solani, especially the ester 2-(2-({(1-(4-chlorophenyl)-1H-pyrazol-3-yl)-oxy}methyl)phenyl)-2-(methoxyimino)acetate, which displayed greater activity than control compound pyraclostrobin at a dosage of 0.1 μg mL-1. The relationship between structure and fungicidal activity was discussed. Density functional theory studies of the 3-methyl heterocyclic ester and the 4-chorophenyl heterocyclic N-methylamide were carried out and the results discussed in terms of the wide difference in fungicidal activity shown by each compound.

Synthesis, crystal structure and fungicidal activities of new type oxazolidinone-based strobilurin analogues

A series of oxazolidinone-based strobilurin analogues were efficiently synthesized by the reaction of 3-(2-bromomethylphenyl) oxazolidin-2-one with 1-substituted phenyl-2H-pyrazolin-3-one. Their structures were confirmed and characterized by 1H-NMR, 13C-NMR, elemental analysis, and mass spectroscopy. In addition, the crystal structure of the target compound 3-(2-((1-phenyl-2H-pyrazol-3-yloxy)methyl)phenyl) oxazolidin-2-one was determined by single crystal X-ray diffraction. The bioassay results of these compounds indicated that some of the oxazolidin-2-one derivatives containing N-substituted phenyl 2H-pyrazol ring exhibited potential in vivo fungicidal activities against M. grisea at the dosage of 1 g L-1.