502496-27-7

Basic information

• Product Name: 3,5-Difluorophenylhydrazine hydrochloride
• Synonyms: 3,5-DIFLUOROPHENYLHYDRAZINE HCL;TIMTEC-BB SBB003744;3,5-Difluorophenylhydrazine hydrochloride;Hydrazine, (3,5-difluorophenyl)-, hydrochloride (1:1);1,3-Difluoro-5-hydrazinobenzene hydrochloride
• CAS NO: 502496-27-7
• Molecular Formula: C6H7ClF2N2
• Molecular Weight: 180.58
• Product Categories: Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes
• Mol File: 502496-27-7.mol
• Article Data: 1

Chemical Properties

• Melting Point: 261-266 °C(lit.)
• Boiling Point: 197.9 °C at 760 mmHg
• Flash Point: 73.5 °C
• Appearance: /
• Density: 1.379g/cm³
• Vapor Pressure: 0.37mmHg at 25°C
• Refractive Index: 1.579
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: 3,5-Difluorophenylhydrazine hydrochloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-Difluorophenylhydrazine hydrochloride(502496-27-7)
• EPA Substance Registry System: 3,5-Difluorophenylhydrazine hydrochloride(502496-27-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 502496-27-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C6H6F2N2/c7-4-1-5(8)3-6(2-4)10-9/h1-3,10H,9H2

Upstream product

• 461-96-1 3,5-difluorobromobenzene 

Downstream Products

• 1062067-18-8 C₂₆H₂₇F₂N₅O₆S 
• 1062067-20-2 C₂₆H₂₇F₂N₅O₆S 
• 1062091-51-3 C₂₆H₂₉F₂N₅O₄S 
• 1062072-52-9 C₂₆H₂₉F₂N₅O₄S 

Relevant articles and documents

Synthesis of Aryl Hydrazines via CuI/BMPO Catalyzed Cross-Coupling of Aryl Halides with Hydrazine Hydrate in Water

The N,N’-bis(2,6-dimethylphenyl)oxalamide was discovered as a powerful ligand for Cu-catalyzed cross-coupling of aryl halides with hydrazine hydrate, leading to the formation of a variety of aryl hydrazines at 80 oC in water under the assistance of K3PO4 and 4 mol% cetyltrimethylammonium bromide from aryl bromides and aryl iodides. Good to excellent yields were observed in most cases.