502506-57-2

Upstream product

• 42383-61-9 2-aminoimidazolesulfate 
• 83-13-6 diethyl 2-phenylmalonate 

Downstream Products

• 1355240-85-5 (1-{4-[3-(4-fluorophenyl)-6-phenyl-imidazo[1,2-a]pyrimidin-7-yl]phenyl}cyclobutyl)carbamic acid tert-butyl ester 
• 1355240-46-8 (7-chloro-6-phenyl-imidazo[1,2-a]pyrimidin-5-yl)cyclopropylamine 
• 1355240-44-6 {1-[4-(5-cyclopropylamino-6-phenyl-imidazo[1,2-a]pyrimidin-7-yl)phenyl]cyclobutyl}carbamic acid tert-butyl ester 
• 1247897-86-4 {1-[4-(6-phenyl-imidazo[1,2-a]pyrimidin-7-yl)phenyl]cyclobutyl}carbamic acid tert-butyl ester 
• 1355240-23-1 1-{4-[3-(4-fluorophenyl)-6-phenyl-imidazo[1,2-a]pyrimidin-7-yl]phenyl}cyclobutylamine 
• 1355240-89-9 (1-{4-[3-(4-methanesulfonyl-phenyl)-6-phenyl-imidazo[1,2-a]pyrimidin-7-yl]phenyl}cyclobutyl)carbamic acid tert-butyl ester 
• 1247897-89-7 {1-[4-(3-bromo-6-phenyl-imidazo[1,2-a]pyrimidin-7-yl)phenyl]cyclobutyl}carbamic acid tert-butyl ester 
• 1355239-89-2 1-{4-[3-(4-methansulfonyl-phenyl)-6-phenyl-imidazo[1,2-a]pyrimidin-7-yl]phenyl}cyclobutylamine 
• 1355239-62-1 {7-[4-(1-amino-cyclobutyl)phenyl]-6-phenyl-imidazo[1,2-a]pyrimidin-5-yl}cyclopropylamine 
• 1247894-84-3 1-[4-(6-phenyl-imidazo[1,2-a]pyrimidin-7-yl)phenyl]cyclobutylamine 
• 1116116-40-5 7-chloro-6-phenylimidazo[1,2-a]pyrimidine 
• 915278-12-5 6-phenylimidazo[1,2-a]pyrimidine 
• 502506-42-5 5,7-dichloro-6-phenylimidazo[1,2-a]pyrimidine 

Relevant academic research and scientific papers

BICYCLIC PYRIMIDINES

Compounds of formula (I), which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.

FUSED PYRIMIDINES

Compounds of formula (I), or an N-oxide, a salt, a tautomer or a stereoisomer of said compound, or a salt of said N-oxide, tautomer or stereoisomer, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6, R7, m and n have the meanings as given in the description and the claims, which are effective inhibitors of the Pi3K/Akt pathway, processes for their production and their use as pharmaceuticals.

FUSED BICYCLIC PYRIMIDINES

Compounds of formula (I), a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.

FUSED BICYCLIC PYRIMIDINES

Compounds of formula (I) a tautomer or stereoisomer thereof, or a salt thereof, wherein ring B and the pyrimidine to which it is fused, R4, R5, R6 and R7 have the meanings as given in the description and the claims, are effective inhibitors of the Pi3K/Akt pathway.