502651-65-2

Basic information

• Product Name: 6-ISO-PROPYL-3H-THIENO[2,3-D]PYRIMIDIN-4-ONE
• Synonyms: AKOS MSC-0516;6-ISO-PROPYL-3H-THIENO[2,3-D]PYRIMIDIN-4-ONE;6-Isopropyl-4a,7a-dihydrothieno[2,3-d]pyrimidin-4(3H)-one
• CAS NO: 502651-65-2
• Molecular Formula: C₉H₁₀N₂OS
• Molecular Weight: 194.25
• Mol File: 502651-65-2.mol
• Article Data: 3

Chemical Properties

• Melting Point: 201-203°C
• Appearance: /
• CAS DataBase Reference: 6-ISO-PROPYL-3H-THIENO[2,3-D]PYRIMIDIN-4-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 6-ISO-PROPYL-3H-THIENO[2,3-D]PYRIMIDIN-4-ONE(502651-65-2)
• EPA Substance Registry System: 6-ISO-PROPYL-3H-THIENO[2,3-D]PYRIMIDIN-4-ONE(502651-65-2)

Safety Data

• Statements: 20/21/22
• Safety Statements: 24/25-36/37
• Hazardous Substances Data: 502651-65-2(Hazardous Substances Data)

Usage

Chemical Properties

White crystal

Upstream product

• 77287-34-4 formamide 
• 149587-85-9 2-amino-5-isopropylthiophene-3-carboxylic acid methyl ester 

Downstream Products

• 439692-52-1 4-chloro-6-(propan-2-yl)thieno[2,3-d]pyrimidine 

Relevant articles and documents

Discovery of novel thieno[2,3-d]pyrimidin-4-yl hydrazone-based inhibitors of Cyclin D1-CDK4: Synthesis, biological evaluation, and structure-activity relationships

The synthesis and evaluation of new analogues of thieno[2,3-d]pyrimidin-4-yl hydrazones are described. 2-Pyrdinecarboxaldehyde [6-(tert-butyl)thieno[2,3-d]pyrimidine-4-yl]hydrazone derivatives have been identified as cyclin-dependent kinase 4 (CDK4) inhibitors. The potency, selectivity profile, and structure-activity relationship of this series of compounds are discussed.

Piperidinylamino-thieno[2,3-D] pyrimidine compounds

The invention relates to 5-HT receptor modulators, particularly 5-HT2B antagonists. Novel piperidinylamino-thieno [2,3-d] pyrimidine compounds represented by Formula I, II and III, and uses thereof for treating conditions including pulmonary ar