5027-77-0

Usage

Uses

Used in Fragrance and Flavor Industry:
Ethyl pyrrolidin-2-yl-acetate is used as a fragrance and flavoring agent for its sweet, floral odor and ability to enhance and prolong the scent of various products. It is commonly found in perfumes, soaps, and detergents.
Used in Food and Beverage Industry:
Ethyl pyrrolidin-2-yl-acetate is used as a flavoring agent in food and beverages, adding a fruity and floral note to the final product.
Used in Pharmaceutical Industry:
Ethyl pyrrolidin-2-yl-acetate is used in the production of pharmaceuticals, specifically in the manufacturing of certain drugs and medications. Its versatility makes it an important ingredient in this industry.

InChI:InChI=1/C8H15NO2/c1-2-11-8(10)6-7-4-3-5-9-7/h7,9H,2-6H2,1H3

Upstream product

• 4778-25-0 (1H-pyrrol-2-yl)acetic acid ethyl ester 
• 1071-46-1 hydrogen ethyl malonate 
• 5981-17-9 dodecahydro-3a,6a,9a-triaza-trindene 
• 1008751-73-2 t-butyl (E)-5-(ethoxycarbonyl)pent-4-enylcarbamate 

Downstream Products

• 78178-75-3 ethyl 1-<2-carbethoxy-2-(4'-benzyloxy-3'-methoxyphenyl)ethyl>pyrrolidinyl-2-acetate 
• 118758-56-8 tert-butyl 2-(2-ethoxy-2-oxoethyl)pyrrolidine-1-carboxylate 
• 136272-85-0 3-(1-pyrrolidinyl)-1-(3-trifluoromethylphenyl)-1,8-naphthyridin-2(1H)-one 
• 35620-60-1 1-carbethoxy-2,3-dioxopyrrolizidine 
• 194154-91-1 (+/-)-1-(tert-Butoxycarbonyl)pyrrolidine-2-acetic acid 

Relevant academic research and scientific papers

First synthesis of pyrrolo[1,2:1′,2′]azepino[5,6-b]indole derivatives

A new family of pyrrolo[1,2:1′,2′]azepino[5,6-b]indole derivatives 8,15 related to anthramycin skeleton was prepared in good yield from indole-2-carboxylic acid and β-aminoesters 4 through intramolecular cyclisation.

Total synthesis of tetracyclic kynurenic acid analogues isolated from chestnut honey

A short and efficient synthesis of novel tetracyclic Kynurenic acid analogues, isolated from chestnut honey, is described. The crucial step of the strategy was a MW-assisted cyclization of enamines of ethyl dioxohexahydropyrrolizine and 2,3-dioxooctahydroindolizine carboxylates to obtain 2,3,6,11b-tetrahydro-1H-pyrrolizino[2,1-b]quinoline-5,11-dione and 5,8,91,011,11a-hexahydroindolizino[2,1-b]quinoline-6,12-dione, respectively. Because of its modular nature, the synthetic strategy can have value as a general method for the preparation of compounds containing these new heterocyclic scaffolds.

Angiotensin II antagonists

This invention provides novel heterocyclic derivatives, their pharmaceutical formulations, and their use for antagonizing angiotensin II receptors in mammals.

Angiotensin II antagonist intermediates

This invention provides novel heterocyclic derivatives, their pharmaceutical formulations, and their use for antagonizing angiotensin II receptors in mammals.

Decarboxylation Reaction. X. Introduction of a Carbon unit at the α-Position of Amines by Reaction of Hexahydro-1,3,5-triazines with Carboxylic Acids

An efficient method for introducing a carbon unit at the α-position of alicyclic amines is described.The method involves the reaction of monocyclic or tetracyclic hexahydro-1,3,5-triazines with trichloroacetic acid, cyanoacetic acid, malonic acid and their derivatives, which are introduced into the α-position of amines in the decarboxylated form.Keywords --- 1,3,5-trialkylhexahydro-1,3,5-triazine; trimer of alicyclic imine; decarboxylation; β-amino acid; carboxylic acid

INTRODUCTION OF CARBON UNIT AT THE α-POSITION OF ALICYCLIC AMINES UTILIZING A DECARBOXYLATION REACTION WITH MALONIC ACID DERIVATIVES

A new method for introducing carbon unit at the α-position of alicyclic amines has been exploited.The method involves a reaction of trimers of alicyclic imines with malonic acid derivatives, of which decarboxylation leads to a formation of carbon-carbon bond at the α-position of alicyclic amines.