502927-14-2Relevant academic research and scientific papers
A nucleophilic addition ring closure [NARC]-based synthesis of (+) -nonactic acid
Fraser, Benjamin,Perlmutter, Patrick
, p. 2896 - 2899 (2002)
Nonactic acid 1 has been synthesized in 12 steps from readily available (S)-(-)-ethyl lactate in 20% overall yield. The key ("NARC") sequence in this method involved anti-aldol addition of acylsultam 3 with aldehyde 4 followed by intramolecular oxymercura
