50298-88-9

Basic information

• Product Name: 17,18-Dehydroapovinvamine
• Synonyms: 17,18-Dehydroapovinvamine
• CAS NO: 50298-88-9
• Molecular Formula: C21H22N2O2
• Molecular Weight: 334.41
• Mol File: 50298-88-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 17,18-Dehydroapovinvamine(CAS DataBase Reference)
• NIST Chemistry Reference: 17,18-Dehydroapovinvamine(50298-88-9)
• EPA Substance Registry System: 17,18-Dehydroapovinvamine(50298-88-9)

Safety Data

• Hazardous Substances Data: 50298-88-9(Hazardous Substances Data)

Usage

Uses

17,18-Dehydroapovincamine is an impurity of Vincamine (V314030), a nootropic agent to combat the effects of aging, or in conjunction with other nootropics (such as piracetam) for a variety of purposes. Vincamine is a peripheral vasodilator that increases blood flow to the brain.

Upstream product

• 4429-63-4 tabersonine 

Relevant articles and documents

Synthesis of new eburnamine-type alkaloid via direct hydroalkoxylation

This study concerns the preparation of a new eburnamine-type alkaloid, methyl (3α,14β,15β,16α)-17,18-didehydro-14,15- dihydroeburnamine-15-methoxy-14-carboxylate (VIII). This alkaloid was prepared from (+)-17,18-dehydroapovincamine (V) using Lewis acid and/or ion exchange resin as catalyst. The hydroalkoxylation reaction of V with methanol was investigated in terms of catalyst, solvent, temperature, and time of reaction. A one-pot method for synthetising this alkaloid was established. The optimal conditions for the reaction are discussed.