50299-12-2

Basic information

• Product Name: H-THR-LEU-OH
• Synonyms: L-THREONYL-L-LEUCINE;L-THR-LEU;H-THR-LEU-OH;THR-LEU
• CAS NO: 50299-12-2
• Molecular Formula: C10H20N2O4
• Molecular Weight: 232.28
• Product Categories: Dipeptides;Dipeptides and Tripeptides;Peptides
• Mol File: 50299-12-2.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: −20°C
• Solubility: Methanol (Slightly, Sonicated)
• CAS DataBase Reference: H-THR-LEU-OH(CAS DataBase Reference)
• NIST Chemistry Reference: H-THR-LEU-OH(50299-12-2)
• EPA Substance Registry System: H-THR-LEU-OH(50299-12-2)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 50299-12-2(Hazardous Substances Data)

Usage

General Description

H-Thr-Leu-OH, also known as Threonine Leucine, is a dipeptide consisting of two amino acids: threonine and leucine. These are two of the twenty standard amino acids used in the synthesis of proteins in living organisms. Threonine is an essential amino acid, meaning it cannot be produced by the organism and must be obtained through the diet. It plays a key role in the proper functioning of the immune system and in promoting heart health. Leucine, on the other hand, directly stimulates muscle protein synthesis, making it highly useful in bodybuilding and strength training activities. The "OH" refers to a hydroxyl group, a molecule consisting of an oxygen atom and a hydrogen atom, commonly found in numerous organic compounds. H-THR-LEU-OH is usually supplied in someone’s natural diet but can also be supplemented.

Relevant articles and documents

DPP4 INHIBITOR AND PHARMACEUTICAL APPLICATION THEREOF

The present invention provides a Dpp4 inhibitor which comprises a leucine derivative of the following formula (1) or a methionine derivative of the following formula (2): wherein each R1 and R3 represents a hydrogen atom (H) and an L-amino acid residue; R2 represents a hydroxyl group (OH), alkoxy group having 1 to 6 carbon atoms, amino group (NH2), alkylamino group having 1 to 6 carbon atoms, glycine residue, β-alanine residue, L-amino acid (except for proline, alanine and phenylalanine) residue or L-amino-acid amide (except for proline amide, alanine amide and phenylalanine amide) residue; and R4 represents a hydroxyl group (OH), alkoxy group having 1 to 6 carbon atoms, amino group (NH2), alkylamino group having 1 to 6 carbon atoms, glycine residue, β-alanine residue, L-amino acid (except for proline and alanine) residue or L-amino-acid amide (except for proline amide and alanine amide) residue. These derivatives also act as autophagy regulators.