503025-43-2Relevant academic research and scientific papers
Enantiomerically Enriched α-Borylzinc Reagents by Nickel-Catalyzed Carbozincation of Vinylboronic Esters
Chen, Jingjia,Hu, Weipeng,Jin, Jing,Lovinger, Gabriel J.,Morken, James P.,Zhang, Chenlong
, p. 14189 - 14195 (2021/09/11)
In this paper is described a synthesis of enantiomerically enriched, configurationally stable organozinc reagents by catalytic enantioselective carbozincation of a vinylboronic ester. This process furnishes enantiomerically enriched α-borylzinc intermediates that are shown to undergo stereospecific reactions, producing enantioenriched secondary boronic ester products. The properties of the intermediate α-borylzinc reagent are probed and the synthetic utility of the products is demonstrated by application to the synthesis of (-)-aphanorphine and (-)-enterolactone.
Nitroalkenes as carbonyl surrogates in arylmethyl-homoallylic alcohol forming one-pot allylation reactions in water
Lin, Mei-Huey,Lin, Wei-Cheng,Liu, Han-Jun,Chuang, Tsung-Hsun
, p. 1278 - 1282 (2013/03/28)
A simple and practical approach has been developed for conducting direct, homoallylic alcohol forming allylation reactions of nitroalkenes in water. Employing the new method, various arylmethyl-homoallylic alcohols can be produced from the corresponding, readily prepared β-nitrostyrenes.
Tin mediated allylation reactions of enol ethers in water
Lin, Mei-Huey,Hung, Shiang-Fu,Lin, Long-Zhi,Tsai, Wen-Shing,Chuang, Tsung-Hsun
supporting information; experimental part, p. 332 - 335 (2011/03/23)
Under tin-mediated Barbier-type reaction conditions, hydration of enol ethers takes place to form aldehydes that undergo allylation reactions. By using this process, various homoallylic alcohols and 2-halohomoallylic alcohols are produced in good to excel
