503159-56-6Relevant articles and documents
Synthesis of a spacer-armed disulfated tetrasaccharide of SB1a, a carbohydrate hapten associated with human hepatocellular carcinoma
Li, Qin,Li, Hui,Li, Qing,Lou, Qing-Hua,Su, Bin,Cai, Meng-Shen,Li, Zhong-Jun
, p. 1929 - 1934 (2002)
A disulfated tetrasaccharide fragment with a spacer arm of human hepatocellular carcinoma carbohydrate antigen SB1a, namely, 2-aminoethyl 3-O-sulfo-β-D-galactopyranosyl-(1→3)-2-acetamido-2-deoxy-β-D- galactopyranosyl-(1→4)-3-O-sulfo-β-D-galactopyranosyl-(1→4)- β-D-glucopyranoside was synthesized via a [2+1+1] block building mode. In the last coupling step toward the trisaccharide acceptor 8, benzoyl protected galactosyl bromide donor 14 was found to be much more reactive than the acetyl-protected donors.