503160-54-1

Upstream product

• 769-42-6 1,3-dimethylbarbituric acid 
• 119072-55-8 tert-butylisonitrile 
• 555-16-8 4-nitrobenzaldehdye 

Relevant academic research and scientific papers

One-pot three component condensation reaction in water: An efficient and improved procedure for the synthesis of furo[2,3-d]pyrimidine-2,4(1H,3H)-diones

The environment-friendly three component condensation reactions of N,N′-dimethylbarbituric acid, 4-nitrobenzaldehyde and alkyl or aryl isocyanides to afford the corresponding furo[2,3-d]pyrimidine-2,4(1H,3H)-diones, in water, in high yields aft

Microwave-assisted three-component condensation on montmorillonite K10: Solvent-free synthesis of furopyrimidines, furocoumarins, and furopyranones

Rapid and efficient one-pot three-component condensation synthesis of furopyrimidines, furocoumarins, and furopyranones are described which occur in the presence of montmorillonite K10 using microwave irradiation under solvent-free conditions.

A simple and convenient approach to the synthesis of aminofuropyrimidindiones

The one-pot three-component reactions of 1,3-dimethylbarbituric acid, aromatic aldehydes and alkyl or aryl isocyanides proceed smoothly at room temperature to give the corresponding 5-aryl-6-alkyl or arylamino-1,3- dimethylfuro [2,3-d] pyrimidine-2, 4 (1H,3H)-dione derivatives in good to excellent yields within 30 minutes in DMF. This three-component reaction represents a facile and efficient route to the described biologically interesting molecules.

Ionic liquid promoted one-pot synthesis of furo[2,3-d]pyrimidine-2,4(1H,3H) -diones

The three-component condensation of aldehyde, N,N′-dimethylbarbituric acid and alkyl or aryl isocyanide afforded the corresponding furo[2,3-d]pyrimidine-2,4(1H,3H)-diones in 1-butyl-3-methylimidazolium bromide as an ionic liquid in high yields at room tem