503269-60-1

Basic information

• Product Name: Cyclopentanone, 2-(2-methoxy-5-methylphenyl)-2-methyl-, (2R)-
• CAS NO: 503269-60-1
• Molecular Formula: C14H18O2
• Molecular Weight: 218.296
• Mol File: 503269-60-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Cyclopentanone, 2-(2-methoxy-5-methylphenyl)-2-methyl-, (2R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclopentanone, 2-(2-methoxy-5-methylphenyl)-2-methyl-, (2R)-(503269-60-1)
• EPA Substance Registry System: Cyclopentanone, 2-(2-methoxy-5-methylphenyl)-2-methyl-, (2R)-(503269-60-1)

Safety Data

• Hazardous Substances Data: 503269-60-1(Hazardous Substances Data)

Upstream product

• 582321-39-9 3-(2-methoxy-5-methylphenyl)-2-methylcyclopent-2-en-1-one 
• 582321-40-2 (1R)-2-methyl-3-(2-methoxy-5-methyl)phenyl-2-cyclopenten-1-ol 
• 22117-97-1 3-isobutoxy-2-methyl-2-cyclopenten-1-one 
• 765-69-5 2-Methylcyclopentane-1,3-dione 
• 582321-43-5 (1R,3R)-3-methyl-3-(2-methoxy-5-methyl)phenyl-2-oxocyclopentyl 4-methylbenzenesulfonate 
• 582321-41-3 (-)-(1R,2R,5R)-1-methyl-5-(2-methoxy-5-methyl)phenyl-6-oxabicyclo[3.1.0]hexan-2-ol 

Downstream Products

• 582321-46-8 2-(2-methoxy-5-methyl)phenyl-1,2-dimethylbicyclo[3.1.0]hexane 
• 582321-45-7 (3S)-2,3-dimethyl-3-(2-methoxy-5-methyl)phenyl-cyclopent-1-ene 
• 81784-13-6 (1S)-1,2,2-trimethyl-1-(2-methoxy-5-methyl)phenylcyclopentane 
• 81784-10-3 4-methyl-2-[(1S)-1,2,2-trimethylcyclopentyl]phenol 
• 582321-44-6 (1R,2R)-1,2-dimethyl-2-(2-methoxy-5-methyl)phenyl-cyclopentanol 
• 220106-58-1 1-methoxy-4-methyl-2-(1,2,2-trimethylcyclopentyl)-benzene 

Relevant articles and documents

Catalytic Asymmetric Construction of α-Quaternary Cyclopentanones and Its Application to the Syntheses of (-)-1,14-Herbertenediol and (-)-Aphanorphine

A novel and efficient strategy to build α-benzylic quaternary cyclopentanones with excellent enantioselectivities (up to 96% ee) and high yields (up to 99% yield) has been developed, and its application demonstrated by the first catalytic asymmetric total synthesis of (-)-1,14-herbertenediol and the formal synthesis of (-)-aphanorphine. Herbertene rides again: A novel and efficient strategy to build α-quaternary cyclopentanones with high yields and excellent enantioselectivities (up to 96% ee) has been developed. Its application is demonstrated by the first catalytic asymmetric total synthesis of (-)-1,14-herbertenediol and the formal synthesis of (-)-aphanorphine.