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Upstream product

• 464-49-3 (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one 
• 1122-91-4 4-bromo-benzaldehyde 
• 1233941-20-2 C₁₄H₂₄BrO₄P 

Relevant academic research and scientific papers

Preparation of functionalized cyclic enol phosphates by halogen-magnesium exchange and directed deprotonation reactions

(Figure presented) Cyclic enol phosphates were magnesiated by a halogen/magnesium exchange reaction or deprotonation using TMP-derived magnesium amide bases. The resulting magnesium reagents react readily with a wide range of electrophiles like allyl bromides and acid chlorides or can be used in Pd-catalyzed cross-coupling reactions. Several optically pure enol phosphates were prepared starting from readily available d-(+)-camphor derivatives.

Simple and effective protocol for Claisen-Schmidt condensation of hindered cyclic ketones with aromatic aldehydes

A simple and effective methodology for Claisen-Schmidt condensation of (-)-menthone and other hindered cyclic ketones with aromatic aldehydes under highly basic conditions using a polar aprotic solvent and a strong base (alkali metal hydroxide or an alkoxide) is described and discussed. Georg Thieme Verlag Stuttgart.