503312-33-2

Upstream product

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• 108549-23-1 Dibenzyl N,N-diisopropylphosphoramidite 
• 15548-45-5 (2S,3S,4S,5S,6R)-2-benzyloxy-6-(hydroxymethyl)tetrahydropyran-3,4,5-triol 

Relevant academic research and scientific papers

Membrane-permeant derivatives of mannose-1-phosphate

For treatment of congenital disorder of glycosylation type Ia (CDG-Ia) membrane-permeant derivatives of mannose-1-phosphate are required. Employing biologically cleavable phosphate protecting groups advantageous precursor derivatives could be synthesized

TREATMENT OF CONGENITAL DISORDERS OF GLYCOSYLATION (CDG) USING MANNOSE

The invention relates to mannose 1-phosphate derivatives and to pharmaceutical or dietary agents, which contain the same and which are used for treating disorders of glycosylation and, in particular, for treating CDG-1a. These derivatives comprise the fol