503315-74-0

Basic information

• Product Name: 3-Fluoro-4-nitrobenzyl alcohol 99%
• Synonyms: 3-Fluoro-4-nitrobenzyl alcohol 99%;(3-Fluoro-4-nitrophenyl)methanol, 2-Fluoro-4-(hydroxymethyl)nitrobenzene;3-Fluoro-4-nitrobenzenemethanol;3-Fluoro-4-nitrobenzylalcohol98%;(3-Fluoro-4-nitrophenyl);Structure
• CAS NO: 503315-74-0
• Molecular Formula: C₇H₆FNO₃
• Molecular Weight: 171.1258432
• Mol File: 503315-74-0.mol

Chemical Properties

• Boiling Point: 328.6±27.0 °C(Predicted)
• Appearance: /
• Density: 1.434
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 13.27±0.10(Predicted)
• CAS DataBase Reference: 3-Fluoro-4-nitrobenzyl alcohol 99%(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Fluoro-4-nitrobenzyl alcohol 99%(503315-74-0)
• EPA Substance Registry System: 3-Fluoro-4-nitrobenzyl alcohol 99%(503315-74-0)

Safety Data

• Hazardous Substances Data: 503315-74-0(Hazardous Substances Data)

Usage

Uses

Used in Scientific Research:
3-Fluoro-4-nitrobenzyl alcohol 99% is used as an organic intermediate for the formulation of advanced compounds or materials in scientific research. Its high purity and specific structural features make it valuable in the development of new chemical entities and materials with potential applications in various fields.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-Fluoro-4-nitrobenzyl alcohol 99% is used as a building block for the synthesis of pharmaceutical compounds. Its unique structure and reactivity allow for the creation of new drug candidates with potential therapeutic effects.
Used in Chemical Synthesis:
3-Fluoro-4-nitrobenzyl alcohol 99% is utilized as a key intermediate in the synthesis of various chemical products. Its presence in the molecular structure can impart specific properties to the final product, making it a versatile component in the chemical manufacturing process.
Used in Material Science:
In material science, 3-Fluoro-4-nitrobenzyl alcohol 99% is employed in the development of new materials with tailored properties. Its incorporation into polymers or other materials can enhance their performance, such as improving thermal stability, mechanical strength, or chemical resistance.

Upstream product

• 185629-31-6 methyl 3-fluoro-4-nitrobenzoate 
• 403-21-4 3-fluoro-4-nitrobenzoic acid 

Downstream Products

• 403-21-4 3-fluoro-4-nitrobenzoic acid 
• 1225287-21-7 3-fluoro-4-nitrobenzyl phosphoramide mustard 

Relevant articles and documents

Synthesis route and preparation method of 3-fluorine-4-nitrobenzaldehyde

The invention discloses a new synthetic route of 3-fluorine-4-nitrobenzaldehyde and a preparation method thereof. The preparation method comprises the following steps: adding 3-fluorine-4-nitrobenzoicacid and an acidic catalyst into an organic solvent methanol, stirring at 60 to 80 DEG C for 5 to 12 hours, and carrying out after-treatment to obtain a solid intermediate product 2; adding the intermediate product 2 into an organic solvent II, adding sodium borohydride while uniformly stirring at 0 DEG C, stirring for 0.5 to 1h at 0 DEG C, slowly heating to 60 DEG C, stirring for 2 to 6h, stopping stirring, and carrying out post-treatment to obtain an intermediate product 3; and adding the intermediate product 3 and an oxidant III into an organic solvent IV, heating and refluxing for 3 to 10hours, cooling to 20 to 30 DEG C after the reaction is finished, and carrying out post-treatment on the reaction solution to obtain the product 3-fluorine-4-nitrobenzaldehyde. According to the methoddisclosed by the invention, sodium borohydride which is safe and easy to treat is adopted to replace high-activity ultralow-temperature anhydrous oxygen diisobutyl aluminum hydride for reduction reaction, so that a relatively good effect is achieved, and the compound 3-fluorine-4-nitrobenzaldehyde is safely and efficiently synthesized. The method is simple, the requirements of production equipment are reduced, the cost is controlled, and the method is suitable for industrial production.

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AZOLIDINONE-VINYL FUSED-BENZENE DERIVATIVES

The present invention is related to azolidinedione-vinyl fused-benzene derivatives of formula (I) for the treatment and/or prophylaxis of autoimmune disorders and/or inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, bacterial or viral infections, kidney diseases, platelet aggregation, cancer, graft rejection or lung injuries. Formula (I), wherein A, X, Y, Z, R1 , R2 and n are as described in the description.