50337-14-9Relevant academic research and scientific papers
Unusual products from dirhodium tetraacetylate-catalyzed decomposition of diazoacetylcycloalkanes
Ceccherelli, Paolo,Curini, Massimo,Marcotullio, Maria Carla,Pisani, Emanuela,Rosati, Ornelio,Wenkert, Ernest
, p. 8501 - 8506 (2007/10/03)
Rh2(OAc)4-assisted decompositions of diazoacetylcycloalkanes are shown to yield cycloalkylacetic acids (Wolff rearrangement), unexpected cycloalkylcarboxylic acids and bicyclic ketones (intramolecular C-H bond insertion). Rh2(OCOF3)4-promoted reactions, on the other hand, have furnished bicyclic ketones and ketene dimers.
Conjugate Addition Reactions of α,β-Unsaturated Ketones with Higher Order, Mixed Organocuprate Reagents, R2Cu(CN)Li2
Lipshutz, Bruce H.,Wilhelm, Robert S.,Kozlowski, Joseph A.
, p. 3938 - 3942 (2007/10/02)
Conjugate reactions of mixed cuprates R2Cu(CN)Li2 with α,β-unsaturated ketones are reported.These reagents, in most cases, react extremely rapidly affording the corresponding alkylated ketones in high yields.Attempts at trapping the intermediate enolates appeared to be successful using MeI as electrophile; however, the method is not general and was, therefore, not pursued.The effects of solvent and ligand composition on R2Cu(CN)Li2 as well as on the more highly mixed species RTRRCu(CN)Li2 have been examined.The selectivity of ligand transfer in these latter,second generation organocuprates is also discussed.
