503437-40-9

Upstream product

• 503437-23-8 3,3-dichloro-1-(2,6-dichloro-5-fluoro-3-pyridinyl)-2-propen-1-one 
• 75-31-0 isopropylamine 
• 62-53-3 aniline 

Downstream Products

• 503437-44-3 7-chloro-6-fluoro-2-(isopropylamino)-1-phenyl-1,8-naphthyridin-4(1H)-one 

Relevant academic research and scientific papers

1,6-naphthyridine derivatives and their use to treat diabetes and related disorders

The invention relates generally to naphthyridine derivatives of the formula wherein one of U, X, Y and Z is nitrogen and the others are C—R, where R is hydrogen or a substituent. More specifically, the invention relates to 1,6-naphthyridine derivatives and pharmaceutical compositions containing such derivatives. Methods of the invention comprise administration of a naphthyridine derivative of the invention for the treatment of diabetes and related disorders.