503540-12-3Relevant academic research and scientific papers
A new efficient procedure for asymmetric synthesis of α-aminophosphonic acids via addition of lithiated bis(diethylamino)phosphine borane complex to enantiopure sulfinimines
Mikolajczyk, Marian,Lyzwa, Piotr,Drabowicz, Jozef
, p. 2571 - 2576 (2002)
The addition of lithiated bis(diethylamino)phosphine borane complex to enantiopure p-toluenesulfinimines is highly diastereoselective, affording the corresponding addition products with high efficiency (yields from 72 to 100%). The addition products were readily converted into α-amino-α-arylmethylphosphonic acids with high enantiomeric purities (from 72 to >98%).
