Cas 503555-63-3,8-({[3-chloro-6-(4-methylpiperazin-1-yl)pyridin-2-yl]carbonyl}amino)-1-(4-fluoro-phenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide

503555-63-3

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Basic information

Product Name: 8-({[3-chloro-6-(4-methylpiperazin-1-yl)pyridin-2-yl]carbonyl}amino)-1-(4-fluoro-phenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide
Synonyms: 8-({[3-chloro-6-(4-methylpiperazin-1-yl)pyridin-2-yl]carbonyl}amino)-1-(4-fluoro-phenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide
CAS NO:503555-63-3
Molecular Formula:
Molecular Weight: 560.03
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 8-({[3-chloro-6-(4-methylpiperazin-1-yl)pyridin-2-yl]carbonyl}amino)-1-(4-fluoro-phenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide(CAS DataBase Reference)
NIST Chemistry Reference: 8-({[3-chloro-6-(4-methylpiperazin-1-yl)pyridin-2-yl]carbonyl}amino)-1-(4-fluoro-phenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide(503555-63-3)
EPA Substance Registry System: 8-({[3-chloro-6-(4-methylpiperazin-1-yl)pyridin-2-yl]carbonyl}amino)-1-(4-fluoro-phenyl)-4,5-dihydro-1H-benzo[g]indazole-3-carboxamide(503555-63-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 503555-63-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 503555-63-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,3,5,5 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 503555-63:
(8*5)+(7*0)+(6*3)+(5*5)+(4*5)+(3*5)+(2*6)+(1*3)=133
133 % 10 = 3
So 503555-63-3 is a valid CAS Registry Number.

503555-63-3Upstream product

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503555-63-3Relevant academic research and scientific papers

Aminopyridinecarboxamide-based inhibitors: Structure-activity relationship

Bonafoux, Dominique F.,Bonar, Sheri L.,Clare, Michael,Donnelly, Ann M.,Glaenzer, Jeanette L.,Guzova, Julia A.,Huang, He,Kishore, Nandidni N.,Koszyk, Francis J.,Lennon, Patrick J.,Libby, Adam,Mathialagan, Sumathy,Oburn, David S.,Rouw, Sharon A,Sommers, Cynthia D.,Tripp, Catherine S.,Vanella, Lori J.,Weier, Richard,Wolfson, Serge G.,Huang, Horng-Chih

experimental part, p. 403 - 414 (2010/03/25)

Series of aminopyridinecarboxamide-based inhibitors were synthesized and tested against human recombinant IKK-2 and in IL-1β stimulated synovial fibroblasts. The 2-amino-5-chloropyridine-4-carboxamides were identified as the most potent inhibitors with im

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