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3,8-dibenzyl-1-oxo-2,8-diaza-spiro[4.5]decane-2-carboxylic acid tert-butyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

503606-62-0

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503606-62-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 503606-62-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,3,6,0 and 6 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 503606-62:
(8*5)+(7*0)+(6*3)+(5*6)+(4*0)+(3*6)+(2*6)+(1*2)=120
120 % 10 = 0
So 503606-62-0 is a valid CAS Registry Number.

503606-62-0Relevant academic research and scientific papers

Novel spirocyclic pyrrolidones as P2/P1 mimetics in potent inhibitors of HIV-1 protease.

Kazmierski, Wieslaw M,Furfine, Eric,Spaltenstein, Andrew,Wright, Lois L

, p. 3431 - 3433 (2002)

We have developed concise and efficient syntheses of novel spirocyclic pyrrolidones 1-3, which involve the alkylation of pyrrolidone precursor 13 with 1,5-dibromopentane, 16 and 15, followed by an in situ lactamization. Conjugates of 1 and 2 with P1'/P2' hydroxy-indanolamine moiety resulted in novel and potent inhibitors of HIV-1 protease 25 and 26, suggesting that 1 and 2 are novel P2/P1 HIV-PI mimetics.

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