503615-07-4

Basic information

• Product Name: ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate
• Synonyms: ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate;6-(4-Aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylic acid ethyl ester;1H-Pyrazolo[3,4-c]pyridine-3-carboxylic acid, 6-(4-aMinophenyl)-4,5,6,7-tetrahydro-1-(4-Methoxyphenyl)-7-oxo-, ethyl ester;Apixaban interMediate;ethyl 6-(4-aminophenyl)-1-(4-methoxyphenyl)-7-oxo-4,5-dihydropyrazolo[3,4-c]pyridine-3-carboxylate
• CAS NO: 503615-07-4
• Molecular Formula: C22H22N4O4
• Molecular Weight: 406.43448
• EINECS: 1312995-182-4
• Mol File: 503615-07-4.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 651.6±55.0 °C(Predicted)
• Appearance: /
• Density: 1.34±0.1 g/cm3 (20 ºC 760 Torr)
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
• Solubility: Chloroform (Slightly), DMF (Slightly)
• PKA: 4.66±0.10(Predicted)
• CAS DataBase Reference: ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate(503615-07-4)
• EPA Substance Registry System: ethyl 6-(4-aMinophenyl)-1-(4-Methoxyphenyl)-7-oxo-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxylate(503615-07-4)

Safety Data

• Hazardous Substances Data: 503615-07-4(Hazardous Substances Data)

Usage

Physical Form

Solid

Uses

Ethyl 6-?(4-?Aminophenyl)?-?1-?(4-methoxyphenyl)?-?7-?oxo-?4,?5,?6,?7-?tetrahydro-?1H-?pyrazolo[3,?4-?c]?pyridine-?3-?carboxylate is an impurity of Apixaban (A726700), A potent, direct, selective, and orally active inhibitor of coagulation factor Xa. It is a potential new oral coagulant that may be useful prevention of venous thromboembolism in total hip, knee replacement orthopedic surgery and stroke in treatment of patient with venous thromboembolic disorder or with atrial fibrillation.