503617-68-3

Basic information

• Product Name: 1H-Indole-2-carboxamide,N-(6-methyl-2-pyridinyl)-(9CI)
• Synonyms: 1H-Indole-2-carboxamide,N-(6-methyl-2-pyridinyl)-(9CI)
• CAS NO: 503617-68-3
• Molecular Formula: C₁₅H₁₃N₃O
• Molecular Weight: 251.28322
• Product Categories: AMIDE
• Mol File: 503617-68-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1H-Indole-2-carboxamide,N-(6-methyl-2-pyridinyl)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-2-carboxamide,N-(6-methyl-2-pyridinyl)-(9CI)(503617-68-3)
• EPA Substance Registry System: 1H-Indole-2-carboxamide,N-(6-methyl-2-pyridinyl)-(9CI)(503617-68-3)

Safety Data

• Hazardous Substances Data: 503617-68-3(Hazardous Substances Data)

Upstream product

• 1477-50-5 Indole-2-carboxylic acid 
• 1824-81-3 2-Amino-6-methylpyridine 
• 58881-45-1 Indole-2-carbonyl chloride 

Relevant articles and documents

Design and synthesis of novel heterobiaryl amides as metabotropic glutamate receptor subtype 5 antagonists

A series of heterobiaryl amides was designed and synthesized as novel mGluR5 antagonists. The synthesis using palladium catalyzed Suzuki-Miyaura cross-coupling reactions provided an array of compounds with a range of in vitro activities. In particular, compound 9e, 4(3,5-difluorophenyl)-N-(6-methylpyridin-1-yl)picolinamide, exhibited nanomolar affinity at the mGluR5 and will serve as a template for future drug design.