503818-15-3

Upstream product

• 79027-28-4 (2S)-3-(benzyloxy)-2-methylpropanal 
• 349655-04-5 1,1-diisopropyloxy-2,2-dimethyl-3-pentanone 

Downstream Products

• 637003-75-9 9-benzyloxy-4,4,6,8-tetramethyl-5-oxo-7-(2,2,2-trichloroethoxycarbonyloxy)-3-(triethylsilanyloxy)nonanoic acid tert-butyl ester 
• 666739-82-8 9-benzyloxy-3-(triethylsilanyloxy)-7-hydroxy-4,4,6,8-tetramethyl-5-oxo-nonanoic acid tert-butyl ester 
• 637003-55-5 9-benzyloxy-3-hydroxy-4,4,6,8-tetramethyl-5-oxo-7-(2,2,2-trichloroethoxycarbonyloxy)nonanoic acid tert-butyl ester 
• 666739-65-7 9-benzyloxy-4,4,6,8-tetramethyl-3,5-dioxo-7-(2,2,2-trichloroethoxycarbonyloxy)nonanoic acid tert-butyl ester 
• 637003-53-3 9-benzyloxy-4,4,6,8-tetramethyl-3,5-dioxo-7-(2,2,2-trichloroethoxycarbonyloxy)nonanoic acid tert-butyl ester 
• 637003-51-1 carbonic acid [1-(2-benzyloxy-1-methylethyl)-2,4,4-trimethyl-3,5-dioxopentyl ester] 2,2,2-trichloroethyl ester 
• 503818-24-4 9-benzyloxy-7-(tert-butyldimethylsilanyloxy)-3-(triethylsilanyloxy)-4,4,6,8-tetramethyl-5-oxononanoic acid tert-butyl ester 
• 666739-81-7 carbonic acid [1-(2-benzyloxy-1-methylethyl)-5,5-diisopropoxy-2,4,4-trimethyl-3-oxopentyl ester] 2,2,2-trichloroethyl ester 

Relevant academic research and scientific papers

SYNTHESIS OF EPOTHILONES, INTERMEDIATES THERETO, ANALOGUES AND USES THEREOF

The present invention provides compounds of formula (I): as described generally and in classes and subclasses herein. The present invention additionally provides pharmaceutical compositions comprising compounds of formula (I) and provides methods of treating cancer comprising administering a compound of formula (I).