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2-(2,4-dimethylthiazol-5-yl)acetonitrile, commonly referred to as MTT, is a yellow-colored compound that plays a significant role in biological research. It is widely recognized for its use in colorimetric assays, which are instrumental in measuring cell viability, proliferation, and cytotoxicity. MTT is soluble in organic solvents and maintains stability at room temperature. Its chemical properties include being a potent and selective protonophoric uncoupler of the mitochondrial oxidative phosphorylation system, which contributes to its cytotoxic effects by disrupting mitochondrial function and inducing apoptosis in cells. Furthermore, MTT has been the subject of research for its potential anti-cancer properties, showing promise in inhibiting the growth of cancer cells in vitro. However, due to its potential toxicity and reactivity, caution is advised when handling MTT in a laboratory setting.

50382-35-9

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50382-35-9 Usage

Uses

Used in Biological Research:
2-(2,4-dimethylthiazol-5-yl)acetonitrile is used as a colorimetric assay agent for measuring [cell viability, proliferation, and cytotoxicity] because of its ability to form a purple formazan product upon reduction by mitochondrial dehydrogenases in living cells, which is then measured spectrophotometrically.
Used in Mitochondrial Function Assessment:
MTT is used as a mitochondrial function disruptor for [assessing mitochondrial activity in cells] due to its role as a potent and selective protonophoric uncoupler of the mitochondrial oxidative phosphorylation system.
Used in Cancer Research:
In the field of cancer research, 2-(2,4-dimethylthiazol-5-yl)acetonitrile is used as an anti-cancer agent for [inhibiting the growth of cancer cells in vitro] based on its demonstrated potential to interfere with cancer cell proliferation and induce apoptosis.
Used in Drug Development:
MTT is utilized in drug development processes as a tool for [screening compounds for cytotoxicity], which is crucial for evaluating the safety and efficacy of new pharmaceuticals.
Used in Toxicity Testing:
In the context of toxicity testing, 2-(2,4-dimethylthiazol-5-yl)acetonitrile is used as a reagent for [assessing the toxic effects of substances on cells], providing valuable data on potential health risks associated with various chemicals and compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 50382-35-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,3,8 and 2 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 50382-35:
(7*5)+(6*0)+(5*3)+(4*8)+(3*2)+(2*3)+(1*5)=99
99 % 10 = 9
So 50382-35-9 is a valid CAS Registry Number.
InChI:InChI=1/C7H8N2S/c1-5-7(3-4-8)10-6(2)9-5/h3H2,1-2H3

50382-35-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(2,4-dimethyl-1,3-thiazol-5-yl)acetonitrile

1.2 Other means of identification

Product number -
Other names Ethyl actoacetate propyleneglycol ketal

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:50382-35-9 SDS

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