503834-19-3 Usage
Uses
Used in Pharmaceutical Industry:
(4-Carboxy-3-ethoxy)phenyl Acetic Acid (Repaglinide Impurity) is used as a quality control parameter for the drug Repaglinide. Its presence in the medication must be monitored and controlled to maintain the purity, stability, and overall quality of the drug. This impurity plays a significant role in ensuring the safe use of Repaglinide by patients with type 2 diabetes.
Used in Manufacturing Process:
(4-Carboxy-3-ethoxy)phenyl Acetic Acid (Repaglinide Impurity) is used as a critical parameter in the manufacturing process of Repaglinide. Keeping its levels within acceptable limits is essential to prevent any potential adverse effects on the drug's efficacy and safety. This impurity serves as a key indicator for the successful synthesis and purification of Repaglinide, allowing manufacturers to optimize their production methods and ensure the delivery of a high-quality medication to patients.
Used in Research and Development:
(4-Carboxy-3-ethoxy)phenyl Acetic Acid (Repaglinide Impurity) is used as a subject of study in research and development efforts aimed at improving the synthesis, purification, and overall quality of Repaglinide. Understanding the properties and behavior of this impurity can help researchers develop more efficient methods for its removal or reduction, ultimately leading to a safer and more effective medication for patients with type 2 diabetes.
Check Digit Verification of cas no
The CAS Registry Mumber 503834-19-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,3,8,3 and 4 respectively; the second part has 2 digits, 1 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 503834-19:
(8*5)+(7*0)+(6*3)+(5*8)+(4*3)+(3*4)+(2*1)+(1*9)=133
133 % 10 = 3
So 503834-19-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H14O5/c1-3-17-10-6-8(7-11(13)14)4-5-9(10)12(15)16-2/h4-6H,3,7H2,1-2H3,(H,13,14)
503834-19-3Relevant academic research and scientific papers
Process for the preparation of 3-ethoxy-4-(alkoxy carbonyl)-phenyl acetic acid. (an intermediate of repaglinide)
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Page 4-5; 6, (2008/06/13)
The present invention relates to an improved and convenient process for the preparation of 3-Ethoxy-4-(alkoxy carbonyl)-phenyl acetic acid, which can be represented by formula (Ia) where R1 represents ethyl or methyl. Specifically the present invention relates to an improved process for the preparation of compound of formula (Ia), which is the key intermediate for Repaglinide of formula (I), by the process, which involves non-hazardous raw materials with an easy handling, and cost effective process
