503842-36-2

Upstream product

• 554-00-7 2,4-Dichloroaniline 
• 2213-43-6 1-Aminopiperidine 
• 503842-31-7 2,4-dioxo-[1,1']bipiperidinyl-3-carboxylic acid ethyl ester 
• 503842-30-6 N-(2-methoxycarbonylethyl)-N-piperidin-1-yl-malonamic acid ethyl ester 
• 503842-32-8 [1,1']bipiperidinyl-2,4-dione 
• 71365-42-9 3-(piperidin-1-ylamino)-propionic acid methyl ester 
• 503842-34-0 1-(2,4-dichloro-phenylamino)-propan-2-one 
• 503842-33-9 1-(2,4-dichloro-phenyl)-3-methyl-5-piperidin-1-yl-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridine-4-one 

Downstream Products

• 1068657-75-9 4-[1-(2,4-dichlorophenyl)-3-methyl-4-oxo-5-piperidin-1-yl-4,5,6,7-tetrahydro-1H-pyrrolo[3,2-c]pyridin-2-yl]benzaldehyde 
• 932739-13-4 1-(2,4-dichlorophenyl)-2-(4-hydroxyphenyl)-3-methyl-5-piperidin-1-yl-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one 

Relevant academic research and scientific papers

PHARMACEUTICAL COMPOSITIONS OF CB1 MODULATORS

The invention relates to a process for the preparation of a stable dispersion of amorphous particles of a CB1 modulator of sub-micron size in an aqueous medium.

Therapeutic Agents 684

Certain 4,5,6,7-tetrahydropyrrolo[3,2-c]pyridin-4-one and 4,5-dihydropyrrolo[3,2-c]pyridin-4-one compounds of formula I, processes for preparing such compounds, their use in the treatment of obesity, psychiatric and neurological disorders, methods for the

Constrained analogs of CB-1 antagonists: 1,5,6,7-Tetrahydro-4H-pyrrolo[3,2-c]pyridine-4-one derivatives

A series of pyrrolopyridinones was designed and synthesized as constrained analogs of the pyrazole CB-1 antagonist rimonabant. Certain examples exhibited very potent hCB-1 receptor binding affinity and functional antagonism with Ki and Kb

THERAPEUTIC AGENTS

The present invention relates to 4, 5, 6, 7 -tetrahydropyrrolo[3,2-c]pyridin-4-one and 4, 5-dihydropyrrolo[3,2-c]pyridin-4-one compounds of formula (I) and processes for preparing such compounds, their use in the treatment of obesity, psychiatric and neur