503843-27-4

Basic information

• Product Name: (2R,6R)-[(1R)-2-hydroxy-1-phenylethyl]-2-methyl-6-undecylpiperidine
• Synonyms: (2R,6R)-[(1R)-2-hydroxy-1-phenylethyl]-2-methyl-6-undecylpiperidine
• CAS NO: 503843-27-4
• Molecular Weight: 373.623
• Mol File: 503843-27-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (2R,6R)-[(1R)-2-hydroxy-1-phenylethyl]-2-methyl-6-undecylpiperidine(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,6R)-[(1R)-2-hydroxy-1-phenylethyl]-2-methyl-6-undecylpiperidine(503843-27-4)
• EPA Substance Registry System: (2R,6R)-[(1R)-2-hydroxy-1-phenylethyl]-2-methyl-6-undecylpiperidine(503843-27-4)

Safety Data

• Hazardous Substances Data: 503843-27-4(Hazardous Substances Data)

Upstream product

• 177981-20-3 (6R)-1-[(1R)-2-hydroxy-1-phenylethyl]-6-methyl-2-piperidone 
• 213828-95-6 (6R)-1-[(1R)-2-(tert-butyldimethylsilyloxy)-1-phenylethyl]-6-methyl-2-piperidinethione 
• 503843-26-3 (6R)-1-[(1R)-2-(tert-butyldimethylsilyloxy)-1-phenylethyl]-6-methyl-2-piperidone 

Downstream Products

• 28720-60-7 (2R,6R)-(-)-2-methyl-6-undecylpiperidine 

Relevant articles and documents

Enantioselective synthesis of piperidine, indolizidine, and quinolizidine alkaloids from a phenylglycinol-derived δ-lactam

Starting from a common lactam, (3R,8aS)-5-oxo-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine (1), or its enantiomer, the enantioselective synthesis of 2-alkylpiperidines and cis- and trans-2,6-dialkylpiperidines is reported. The potential of this approach is illustrated by the synthesis of the piperidine alkaloids (R)-coniine, (2R,6S)-dihydropinidine, (2R,6R)-lupetidine, and (2R,6R)-solenopsin A, the indolizidine alkaloids (5R,8aR)-indolizidine 167B and (3R,5S,8aS)-monomorine I, and the nonnatural base (4R,9aS)-4-methylquinolizidine.