503856-39-1

Basic information

• Product Name: diethyl 5-methyl-2-nitrobenzylphosphonate
• Synonyms: diethyl 5-methyl-2-nitrobenzylphosphonate
• CAS NO: 503856-39-1
• Molecular Weight: 287.252
• Mol File: 503856-39-1.mol

Chemical Properties

• CAS DataBase Reference: diethyl 5-methyl-2-nitrobenzylphosphonate(CAS DataBase Reference)
• NIST Chemistry Reference: diethyl 5-methyl-2-nitrobenzylphosphonate(503856-39-1)
• EPA Substance Registry System: diethyl 5-methyl-2-nitrobenzylphosphonate(503856-39-1)

Safety Data

• Hazardous Substances Data: 503856-39-1(Hazardous Substances Data)

Upstream product

• 66424-92-8 5-methyl-2-nitrobenzyl alcohol 
• 3113-72-2 5-methyl-2-nitrobenzoic acid 
• 110822-05-4 2-(bromomethyl)-4-methyl-1-nitrobenzene 
• 122-52-1 triethyl phosphite 

Downstream Products

• 1422192-97-9 4-methyl-2-((1-(phenylsulfonyl)piperidin-3-ylidene)methyl)aniline 
• 1009631-75-7 9-methyl-2-(phenylsulfonyl)-1,2,3,4,5,6-hexahydroazepino[4,3-b]indole 
• 1431090-02-6 3-(2-azido-5-methoxybenzylidene)-1-Boc-piperidine 
• 303040-34-8 (5-methyl-2-octanoylamino-benzyl)-phosphonic acid diethyl ester 
• 503856-47-1 (2-amino-5-methyl-benzyl)-phosphonic acid diethyl ester 

Relevant articles and documents

Rh2(II)-catalyzed selective aminomethylene migration from styryl azides

Rh2(II)-Carboxylate complexes were discovered to promote the selective migration of aminomethylenes in β,β-disubstituted styryl azides to form 2,3-disubstituted indoles. Mechanistic data are also presented that suggest that the migration occurs stepwise before diffusion of the iminium ion.

Discovery of novel phosphonic acid derivatives as new chemical leads for inhibitors of TNF-α production

2-(Acylamino)benzylphosphonic acid 6 derived from an artificial substrate of sphingomyelinase was found to show inhibitory activity of TNF-α production. Structural optimization was started with the chemical modification of 6. The discovery of another chem