504-12-1

Usage

Uses

Used in Pharmaceutical Industry:
9-AZABICYCLO[3,3,1]NONYL-3-ENDO-OL serves as a crucial precursor in the synthesis of a range of bioactive compounds. Its role in creating new pharmaceuticals is significant, as it can contribute to the development of innovative drugs with potential therapeutic applications.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, 9-AZABICYCLO[3,3,1]NONYL-3-ENDO-OL is utilized as a starting material for the production of various agrochemicals. Its involvement in this industry aids in the creation of substances that can enhance crop protection and contribute to agricultural productivity.
Used in Material Science:
9-AZABICYCLO[3,3,1]NONYL-3-ENDO-OL has also been explored for its potential in the development of new materials. Its unique structural attributes make it a candidate for use in creating advanced materials with specific properties tailored for various applications.
Used as a Chiral Ligand in Asymmetric Catalysis:
In the realm of catalysis, 9-AZABICYCLO[3,3,1]NONYL-3-ENDO-OL has been studied for its potential as a chiral ligand in asymmetric catalysis. This application is vital for enhancing the selectivity and efficiency of chemical reactions, leading to the production of enantiomerically pure compounds, which are essential in various chemical and pharmaceutical processes.
Used in Medicinal Chemistry:
Lastly, 9-AZABICYCLO[3,3,1]NONYL-3-ENDO-OL has been investigated for its role in medicinal chemistry, particularly for the synthesis of novel drugs. Its unique properties and reactivity make it a promising candidate for creating new pharmaceutical agents that could address unmet medical needs.

Upstream product

• 2038-40-6 (3-endo)-9-methyl-9-azabicyclo[3.3.1]nonan-3-ol 
• 552-70-5 pseudopelletierine 
• 70243-51-5 3-endo-hydroxy-9-benzyl-9-azabicyclo[3.3.1]nonane 
• 4390-39-0 9-azabicyclo[3.3.1]nonan-3-one 

Downstream Products

• 854733-35-0 3endo-hydroxy-9-aza-bicyclo[3.3.1]nonane-9-carboxylic acid 
• 934180-37-7 tert-butyl (1R,3r,5S)-3-hydroxy-9-azabicyclo[3.3.1]nonane-9-carboxylate 

Relevant academic research and scientific papers

METHOD FOR PRODUCING ENDO-9-AZABICYCLO[3.3.1]NONAN-3-OL DERIVATIVE

A 9-azabicyclo[3.3.1]nonan-3-one derivative is reacted with a hydrogen in the presence of a catalyst composed of a ruthenium complex to obtain, at a low cost, an endo-9-azabicyclo[3.3.1]nonan-3-ol derivative useful as a production intermediate for agroche

9-AZABICYCLO [3 . 3 . 1] NONANE DERIVATIVES AS MONOAMINE REUPTAKE INHIBITORS

The present invention relates to a 9-azabicyclo[3.3.1]nonane derivative of formula (I), wherein R1 is H or C1-5alkyl; X is O or NR2, wherein R2 is H, C1-5alkyl or C2-5acyl and Ar is C6-10aryl or a 5-10 membered heteroaryl ring system, both being optionally substituted with one to three of R3-R5 independently selected from halogen, C1-5alkyl, C1-5alkoxy, C3-6cycloalkyl, C2-5alkenyl, C2-5alkynyl, CN, NO2, hydroxy, phenyl, phenoxy and phenylC1-2alkoxy, wherein said C1-5alkyl and C1-5alkoxy are optionally substituted with one to three halogens and wherein said phenyl, phenoxy and phenylC1-2alkoxy are optionally substituted with one to three substituents independently selected from halogen and methyl or two of R3-R5 at adjacent positions together form a methylenedioxy or propylene unit, with the proviso that the compounds exo-9-methyl-3-phenoxy-9-azabicyclo[3.3.1]nonane and N-(9-methyl-9-azabicyclo[3.3.1]non-3-yl)-1H indazole-5-amine are excluded, or a pharmaceutically acceptable salt or solvate thereof. The invention also relates to pharmaceutical compositions comprising said 9-azabicyclo[3.3.1]nonane derivatives and to their use in therapy.

9-Azabicyclo[3.3.1]nonane derivatives

The present invention relates to a 9-azabicyclo[3.3.1]nonane derivative of formula I, wherein each of the substituents is given the definition as set forth in the specification and claims, or a pharmaceutically acceptable salt or solvate thereof. The invention also relates to pharmaceutical compositions comprising said 9-azabicyclo[3.3.1]nonane derivatives and to their use in therapy.