5042-34-2Relevant academic research and scientific papers
Practical synthesis of amides from in situ generated copper(I) acetylides and sulfonyl azides
Cassidy, Michael P.,Raushel, Jessica,Fokin, Valery V.
, p. 3154 - 3157 (2007/10/03)
(Chemical Equation Presented) A direct, simple, and efficient route from terminal alkynes to amides is achieved by their copper(I)-catalyzed reaction with sulfonyl azides (see scheme). The reaction proceeds with the in situ generation of copper(I) acetylides and represents a one-step formal oxidative hydration of a triple bond.
