5042-68-2

Upstream product

• 56-41-7 L-alanin 
• 104-15-4 toluene-4-sulfonic acid 

Downstream Products

• 111652-24-5 alanine tosylate 18-Crown-6 complex 
• 93032-72-5 (S)-2-Amino-1-benzoimidazol-1-yl-propan-1-one; compound with toluene-4-sulfonic acid 
• 125982-36-7 (S)-2-Amino-propionic acid 9H-fluoren-9-yl ester; compound with toluene-4-sulfonic acid 

Relevant academic research and scientific papers

The Use of Crown Ethers in Peptide Chemistry. Part 1. Syntheses of Amino Acid Complexes with the Cyclic Polyether 18-Crown-6 and their Oligomerisation in Dicyclohexylcarbodi-imide-containing Solutions

The synthesis of amino acid complexes with the cyclic polyether 18-crown-6 and their solubility properties in organic solvents are described.Oligo homo-amino acid peptides have been prepared using the crown ether complexes and dicyclohexylcarbodi-imide as coupling agent.The mechanism leading to the formation of the oligopeptides has been discussed and proved to involve the transferring of one N-H proton from the crown ether complex to the carbodi-imide nitrogen.

4H-3,1-BENZOXAZIN-4-ONES AND RELATED COMPOUNDS AND USE AS ENZYME INHIBITORS

Novel 2-amino-4H-3,1-benzoxazin-4-ones represented by the formula wherein R 1, R 2, R 3 and X are defined herein are useful as enzyme inhibitors in animals.