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p-TosOH*H-Leu-ODpm is a complex chemical compound that consists of three main components: p-toluenesulfonic acid (p-TosOH), leucine (Leu), and 4,5-dimethoxy-2-phenyl-2-oxazolidinone (ODpm). p-TosOH is a strong acid commonly used as a catalyst in organic synthesis, while leucine is an essential amino acid that plays a crucial role in various biological processes. ODpm is a chiral auxiliary used in asymmetric synthesis to induce enantioselectivity. The combination of these three components in p-TosOH*H-Leu-ODpm results in a unique molecule with potential applications in the fields of organic chemistry, pharmaceuticals, and materials science.

5042-85-3

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5042-85-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5042-85-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,0,4 and 2 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 5042-85:
(6*5)+(5*0)+(4*4)+(3*2)+(2*8)+(1*5)=73
73 % 10 = 3
So 5042-85-3 is a valid CAS Registry Number.

5042-85-3Relevant academic research and scientific papers

Application of 4-Polystyryltriphenylmethyl Chloride to the Syntheses of Peptides and Amino Acid Derivatives

Barlos, Kleomenis,Gatos, Dimitrios,Kallitsis, Ioannis,Papaioannou, Dionysios,Sotiriou, Petros

, p. 1079 - 1082 (2007/10/02)

Use of polymer-bound trityl chloride as an α-amino protecting group of amino acids allows simple and high-yield syntheses of amino acid derivatives and peptides.

A Novel Preparation of Amino Acid Diphenylmethyl Esters and Their Application in Peptide Synthesis

Barlos, Kleomenis,Kallitsis, John,Mamos, Petros,Patrianakou, Stella,Stavropoulos, Georg

, p. 633 - 636 (2007/10/02)

Trityl amino acid diphenylmethyl esters 2 were prepared by Mitsunobu condensation of tritylamino acids 1 with diphenylmethanol using excess triphenylphosphane and diethyl azodicarboxylate.The esters 2 were converted into the corresponding p-toluenesulfonates 3 on treatment with p-toluenesulfonic acid.The removal of the N-trityl group in the presence of the diphenylmethyl ester group is studied by the preparation of leucine-enkephalin (12).Best selectivity is obtained when 1-hydroxybenzotriazole in trifluoroethanol is used as detritylation reagent.

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