50429-40-8Relevant academic research and scientific papers
STEREOCHEMISTRY OF STRICTIC ACID AND RELATED FURANODITERPENES FROM CONYZA JAPONICA AND GRANGEA MADERASPATANA
Pandey, Umesh C.,Singhal, Ashok K.,Barua, Nabin C.,Sharma, R. P.,Baruah, Jogendra N.,et al.
, p. 391 - 398 (1984)
Extraction of Conyza japonica gave strictic acid, ent-2β-hydroxy-15,16-epoxy-3,13(16),14-clerodatrien-18-oic acid and 5,7-dihydroxy-3,8,4'-trimethoxyflavone.Extraction of Grangea maderaspatana gave (-)-hardwickiic acid, ent-15,16-epoxy-1,3,13(16),14-clerodatetraen-18-oic acid and 3-hydroxy-8-acetoxypentadeca-1,9,14-trien-4,6-diyne.The structure of ent-2β-hydroxy-15,16-epoxy-3,13(16),14-clerodatrien-18-oic acid was deduced by spectroscopic methods and by partial synthesis from (-)-hardwickiic acid and the stereochemistries of strictic acid and ent-15,16-epoxy-1,3,13(16),14-clerodatetraen-18-oic acid were established by correlation with ent-2β-hydroxy-15,16-epoxy-3,13(16),14-clerodatrien-18-oic acid. - Keywords: Conyza japonica; Grangea maderaspatana; Compositae; Astereae; strictic acid; clerodanes; 5,7-dihydroxy-3,8,4'-trimethoxyflavone; 3-hydroxy-8-acetoxy-pentadeca-1,9,14-trien-4,6-diyne.
