504433-36-7

Basic information

• Product Name: (S)-N-(2-bromo-3-methyl-2-butenyl)-1-phenylethylamine
• Synonyms: (S)-N-(2-bromo-3-methyl-2-butenyl)-1-phenylethylamine
• CAS NO: 504433-36-7
• Molecular Weight: 268.197
• Mol File: 504433-36-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-N-(2-bromo-3-methyl-2-butenyl)-1-phenylethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-N-(2-bromo-3-methyl-2-butenyl)-1-phenylethylamine(504433-36-7)
• EPA Substance Registry System: (S)-N-(2-bromo-3-methyl-2-butenyl)-1-phenylethylamine(504433-36-7)

Safety Data

• Hazardous Substances Data: 504433-36-7(Hazardous Substances Data)

Upstream product

• 32264-50-9 1,1-dibromo-2,2-dimethylcyclopropane 
• 2627-86-3 (S)-1-phenyl-ethylamine 

Downstream Products

• 504433-37-8 [(S)-1-phenylethyl]-2-(propan-2-ylidene)aziridine 

Relevant articles and documents

Multi-component reactions of 2-isopropylidene-aziridines: Application to the synthesis of enantiopure neopentylamines

Neopentylamines {(1S,1'S)-7a,b} are made from (S)-2-isopropylidene-1-(1-phenylethyl)aziridine (4) in 73% and 56% yields respectively, and as single diastereomers, using a multi-component reaction (M-CR). The structure of (1S,1'S)-7a is confirmed by X-Ray crystallography. Cleavage of the chiral control element {(S)-PhMeCH} from 7a yields neopentyl type amine (8·HC1) (≥95%ee). Further experiments reveal the scope and limitations of this M-CR.