50461-92-2Relevant academic research and scientific papers
Studies of the selective O-alkylation and dealkylation of flavonoids. XIX. A convenient method for synthesizing 3,5,6,7,8-pentaoxygenated flavones
Horie,Kawamura,Yamamoto,Yamashita
, p. 2054 - 2063 (2007/10/03)
The methoxymethyl ethers of 6-hydroxy-5,7,8-trimethoxyflavones, which were derived from 2',5'dihydroxy-3',4',6'-trimethoxyacetophenone, were oxidized with dimethyldioxirane to give the corresponding 3-hydroxyflavones. Selective O-alkylation and dealkylation of the 3-hydroxyflavones were examined and a convenient method for synthesizing the following ten kinds of 3,5,6,7,8- pentaoxygenated flavones was established: 3-hydroxy-5,6,7,8- tetramethoxyflavones, 3,5-dihydroxy-6,7,8-trimethoxyflavones, 3,6-dihydroxy- 5,7,8-trimethoxyflavones, 3,5,6-trihydroxy-7,8-dimethoxyflavones, 3,5,6,7- tetrahydroxy-8-methoxyflavones, and their 3-methyl ethers. Furthermore, 3,5,8-trihydroxy-4',6,7-trimethoxyflavone, 3,8-dihydroxy-4',5,6,7- tetramethoxyflavone, and 5,8-dihydroxy-3,6,7-trimethoxyflavones were similarly synthesized and their spectral properties were examined. Additionally, the proposed structures of three natural flavones were revised.
ACYLATED FLAVONOLS AND OTHER CONSTITUENTS FROM GALEANA PRATENSIS
Maldonado, Emma,Toscano, Ruben A.,Mancera, Claudia,Tripp, Teresa,Ortega, Alfredo
, p. 1003 - 1008 (2007/10/02)
The chemical investigation of Galeana pratensis afforded, in addition to known sesquiterpene lactones, the new acyl flavonoids, pratensins A (5,7-dihydroxy-3,6,4'-trimethoxy-8-tigloyloxyflavone) and B 5,4'-dihydroxy-3,6,7-trimethoxy-8-(2-methylbutyroylox
