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2-Pentanone, 4-methyl-4-(phenylthio)- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

50461-99-9

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50461-99-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 50461-99-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,0,4,6 and 1 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 50461-99:
(7*5)+(6*0)+(5*4)+(4*6)+(3*1)+(2*9)+(1*9)=109
109 % 10 = 9
So 50461-99-9 is a valid CAS Registry Number.

50461-99-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-methyl-4-phenylsulfanylpentan-2-one

1.2 Other means of identification

Product number -
Other names 4-Methyl-4-phenylmercapto-pentan-2-on

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:50461-99-9 SDS

50461-99-9Relevant academic research and scientific papers

Photo-biocatalytic One-Pot Cascades for the Enantioselective Synthesis of 1,3-Mercaptoalkanol Volatile Sulfur Compounds

Lauder, Kate,Toscani, Anita,Qi, Yuyin,Lim, Jesmine,Charnock, Simon J.,Korah, Krupa,Castagnolo, Daniele

supporting information, p. 5803 - 5807 (2018/04/19)

The synthesis of enantiomerically pure 1,3-mercaptoalkanol volatile sulfur compounds through a one-pot photo-biocatalytic cascade reaction is described. Two new KRED biocatalysts with opposite enantioselectivity were discovered and proved to be efficient

Conjugate addition of unactivated thiols to α,β-unsaturated ketones catalyzed by a bifunctional rhenium(V)-oxo complex

Peng, Allan,Rosenblatt, Ross,Nolin, Kristine

supporting information; experimental part, p. 2712 - 2714 (2012/07/14)

ReOCl3(OPPh3)(S(CH3)2) has been found to be an efficient bifunctional catalyst for the 1,4-addition of thiols to α,β-unsaturated ketones. The addition of thiophenol derivatives and alkyl thiols proceeds under mi

Ionic liquid/PPh3 promoted cleavage of diphenyl disulfide and diselenide: A straight-forward metal-free one-pot route to the synthesis of unsymmetrical sulfides and selenides

Banerjee, Subhash,Adak, Laksmikanta,Ranu, Brindaban C.

supporting information; experimental part, p. 2149 - 2152 (2012/05/05)

A metal-free cleavage of diphenyl disulfide and diphenyl diselenide has been achieved using ionic liquid/triphenyl phosphine (PPh3) and a convenient protocol for the one-pot synthesis of unsymmetrical sulfides and selenides by condensing 'in situ' generated thiolate or selenate anion with alkyl halides has been developed. In addition, 1,4-conjugate addition of the generated thiolate anions to activated alkenes has also been demonstrated. The ionic liquid, 1-methyl-3-pentyl imidazolium bromide, [pmIm]Br plays a crucial role in promoting the course of the reactions and shows superior activity and selectivity compared to other solvents. The [pmIm]Br has been reused for at least five times without appreciable loss of activity.

Fluoroboric acid adsorbed on silica-gel (HBF4-SiO2) as a new, highly efficient and reusable heterogeneous catalyst for thia-Michael addition to α,β-unsaturated carbonyl compounds

Sharma, Gaurav,Kumar, Raj,Chakraborti, Asit K.

, p. 4272 - 4275 (2008/09/21)

Fluoroboric acid adsorbed on silica-gel (HBF4-SiO2) has been found to be a new and highly efficient heterogeneous catalyst for thia-Michael addition to α,β-unsaturated carbonyl compounds under solvent-free conditions. In the case of

Scope and limitations of HClO4-SiO2 as an extremely efficient, inexpensive, and reusable catalyst for chemoselective carbon-sulfur bond formation

Khatik, Gopal L.,Sharma, Gaurav,Kumar, Raj,Chakraborti, Asit K.

, p. 1200 - 1210 (2007/10/03)

The scope and limitations of perchloric acid adsorbed on silica gel (HClO4-SiO2) as a highly efficient, inexpensive, and reusable catalyst for chemoselective carbon-sulfur bond formation by conjugate addition of thiols to α,β-unsatur

Efficient synthesis of β-alkyl/arylsulfanyl carbonyl compounds by In-TMSCl-promoted cleavage of dialkyl/diaryl disulfides and subsequent Michael addition

Ranu, Brindaban C.,Mandal, Tanmay

, p. 1517 - 1523 (2008/02/03)

A convenient and efficient procedure for the synthesis of β-alkyl/arylsulfanyl carbonyl compounds has been developed by a simple one-pot reaction of dialkyl/diaryl sulfides with α,β-unsaturated aldehydes, ketones, carboxylic esters, and nitriles in presence of indium and trimethylsilyl chloride under sonication. Copyright Taylor & Francis Group, LLC.

L-proline catalyzed michael additions of thiophenols to α,βunsaturated compounds, particularly α-enones, in the ionic liquid [bmim]PF6

Kotrusz, Peter,Toma, Stefan

, p. 197 - 205 (2007/10/03)

L-Proline catalyzed additions of 13 different thiols to 11 different a-enone Michael acceptors in [bmim] PF6 are reported. Reasonable to high yields of the reaction products were isolated in most cases.

Indium(I) iodide promoted cleavage of dialkyl disulfides - Application of the Michael addition of thiolate anions to conjugated carbonyl compounds and regioselective ring opening of epoxides

Ranu, Brindaban C.,Mandal, Tanmay

, p. 762 - 770 (2007/10/03)

Indium(I) iodide promotes cleavage of dialkyl disulfides generating thiolate anions that then undergo facile addition to α,β-unsaturated ketones, aldehydes, carboxylic esters, and nitriles under neutral conditions producing corresponding β-ketosulfides or β-cyanosulfides. This strategy has also been used for the regioselective nucleophilic ring opening of epoxides by thiolate anions in presence of indium(III) chloride producing corresponding β-hydroxyphenyl sulfides. The reactions are in general, very clean, high yielding, and reasonably fast. Thus, simple and convenient procedures for the synthesis of β-ketosulfides or β-cyanosulfides and β-hydroxyalkyl sulfides have been developed using this cleavage reaction.

Indium(I) iodide-promoted cleavage of dialkyl disulfides and subsequent Michael addition of thiolate anions to conjugated carbonyl compounds

Ranu, Brindaban C.,Mandal, Tanmay

, p. 1239 - 1242 (2007/10/03)

Indium(I) iodide promotes cleavage of dialkyl disulfides generating thiolate anions which then undergo facile addition to α,β-unsaturated ketones, aldehydes, carboxylic esters and nitriles under neutral conditions producing corresponding β-keto or β-cyano

Catalysis by an ionic liquid: Efficient conjugate addition of thiols to electron deficient alkenes catalyzed by molten tetrabutylammonium bromide under solvent-free conditions

Ranu, Brindaban C.,Dey, Suvendu S.,Hajra, Alakananda

, p. 2417 - 2421 (2007/10/03)

An inexpensive and readily available ionic liquid, tetrabutylammonium bromide in the molten state, efficiently catalyzes the conjugate addition of thiols to α,β-unsaturated nitriles, carboxylic ester, ketones and aldehydes as well as nitro olefins.

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