5050-64-6

Upstream product

• 74609-92-0 3,5,5-Triphenyl-4,5-dihydro-isoxazole 2-oxide 
• 614-20-0 3-oxo-3-phenylpropionic acid 
• 91-01-0 1,1-Diphenylmethanol 
• 1669-73-4 1,3,3-triphenyl-propan-1-one oxime 
• 606-86-0 1,3,3-triphenylpropan-1-one 
• 131934-07-1 1,3,3-triphenylpropan-1-one oxime 
• 849-01-4 1,3,3-triphenylprop-2-en-1-one 
• 896-65-1 (1,2-diphenylcyclopropyl)benzene 
• 65642-47-9 1,3,3-triphenyl-propenone oxime 
• 530-48-3 1,1-Diphenylethylene 
• 873-67-6 benzonitrile oxide 

Downstream Products

• 4888-35-1 N-Benzoyl-α-acetyl-β,β-diphenyl-vinylamin 
• 4888-34-0 N-(2-phenylstyryl)benzamide 
• 530-48-3 1,1-Diphenylethylene 

Relevant academic research and scientific papers

Arylboronic Acid Catalyzed Dehydrative Mono-/Dialkylation Reactions of β-Ketoacids and Alcohols

The dehydrative mono-/dialkylation reactions of alcohols and β-ketoacids were realized under arylboronic acid catalysis, furnishing a series of β-aryl ketones and β-ketoesters in yields of 15–99%, with CO2 and H2O being the byproduct

Preparation method of 4, 5-dihydroisoxazole derivative

The invention discloses a preparation method of a 4, 5-dihydroisoxazole derivative, and relates to a prepartion method of a 4, 5-dihydroisoxazole derivative represented by formula (II). The method comprises the steps: reacting hydroxylamine hydrochloride

TEMPO-Mediated Selective Synthesis of Isoxazolines, 5-Hydroxy-2-isoxazolines, and Isoxazoles via Aliphatic δ-C(sp3)-H Bond Oxidation of Oximes

Selective synthesis of three different bioactive heterocycles; isoxazolines, 5-hydroxy-2-isoxazolines and isoxazoles from the same starting material using TEMPO (2,2,6,6-Tetramethylpiperidin-1-oxyl) as a radical initiator is reported. Selectivity was achi

Selectfluor-Bu4NI-Mediated C(sp3)-H Oxidation in Aqueous Media: Synthesis of Δ2-Isoxazolines from Oximes

The direct functionalization of an aliphatic C-H bond within a complex molecule through a free-radical pathway is a valuable tool in synthetic chemistry. Herein, we developed an efficient transition-metal-free approach to generate Δ2-isoxazolines from oximes by radical-mediated C(sp3)-H oxidation. Investigation of the mechanism suggested that in the presence of Selectfluor and Bu4NI, the homolysis of the in situ formed O-I bond generated an iminoxyl radical that facilitated subsequent 1,5-H transfer and C(sp3)-H oxidation. The title reaction involves Selectfluor-Bu4NI-mediated C-O bond formation in aqueous media under metal-free conditions. A variety of Δ2-isoxazolines are directly synthesized from oximes by remote intramolecular functionalization of C(sp3)-H bonds.

TEMPO-mediated aliphatic C-H Oxidation with Oximes and hydrazones

A method for aliphatic C-H bond oxidation of oximes and hydrazones mediated by 2,2,6,6-tetramethylpiperidin-1-oxyl (TEMPO) has been developed, which enables the concise assembly of substituted isoxazole and pyrazole skeletons.

Insertion of Nitrogen Oxide and Nitrosonium Ion into the Cyclopropane Ring: A New Route to 2-Isoxazolines and its Mechanistic Studies

The 9,10-dicyanoanthracene (DCA)-sensitized photoreaction of 1,2-diarylcyclopropanes 1a-d in nitrogen oxide (NO)-saturated CH3CN afforded 3,5-diaryl-2-isoxazolines 2a-d in excellent yields.The reaction of 1a-d with NOBF4 or with a mixture of NO and O2 in

Formation of 2-Substituted 2-Isoxazolinium Salts by the Reaction of 1,1,2,2-Tetrasubstituted Cyclopropanes with NOBF4

The reaction of 1,1,2,2-tetraphenyl- and 1-methyl-1,2,2-triphenylcyclopropanes with NOBF4 gave 2-phenyl-2-isoxazolinium tetrafluoroborates via the phenyl migration from 3-phenyl-2-isoxazolidinium or 1-isoxazolinium intermediates.

Thermal Decomposition of Silver Salts of Aryldinitromethanes in the Presence of Unsaturated Systems. Possible Formation of Arylnitrocarbenes

Decomposition of several silver salts of aryldinitromethanes at 100 deg C in the presence of 1,1-diarylethylenes leads to the formation of Δ2-isoxazoline N-oxides in moderate yields and to Δ2-isoxazolines as byproducts. The spectral data of the new compou