50501-07-0Relevant articles and documents
Organo-Photoredox Catalyzed Oxidative Dehydrogenation of N-Heterocycles
Sahoo, Manoj K.,Jaiswal, Garima,Rana, Jagannath,Balaraman, Ekambaram
supporting information, p. 14167 - 14172 (2017/10/16)
We report here for the first time the catalytic oxidative dehydrogenation of N-heterocycles by a visible-light organo-photoredox catalyst with low catalyst loading (0.1–1 mol %). The reaction proceeds efficiently under base- and additive-free conditions with ambient air at room temperature. The utility of this benign approach is demonstrated by the synthesis of various pharmaceutically relevant N-heteroarenes such as quinoline, quinoxaline, quinazoline, acridine, and indole.
Regiospecific functionalization of indole-2-carboxylates and diastereoselective preparation of the corresponding indolines
Collot, Valerie,Schmitt, Martine,Marwah, Padma,Bourguignon, Jean-Jacques
, p. 2823 - 2847 (2007/10/03)
The N-acyl derivatives of 3-substituted indole-2-carboxylates prepared through several routes were submitted to catalytic hydrogenation affording either cis- or trans-indoline diastereomers after quantitative C-2 epimerization.
Synthesis of 3-phenylindoline-2-carboxamides as semi-rigid phenylalanine mimetics
Collot, Valerie,Schmitt, Martine,Marwah, Ashok K.,Norberg, Bernadette,Bourguignon, Jean-Jacques
, p. 8033 - 8036 (2007/10/03)
Regioselective catalytic hydrogenation of N-acyl 3-phenylindole-2-carboxylates is the key step for tile preparation of cis and trans ndoline-2-carboxamides which can be considered as phenylalanine semi-rigid derivatives.
