505069-72-7Relevant academic research and scientific papers
Synthesis and stability study of a modified phenylpropionic acid linker-based esterase-sensitive prodrug
Song, Xiaoping,Siahaan, Teruna J.
, p. 3439 - 3442 (2002)
An esterase-sensitive amide prodrug 1 with a modified phenylpropionic acid linker was synthesized. The prodrug can be converted to the drug using isolated porcine esterase and human plasma. Paraoxon, an esterase inhibitor, can inhibit prodrug-to-drug conv
