50508-35-5

Basic information

• Product Name: 2-(4-nitrophenoxy1)-1-(piperidin-1-yl)ethanone
• Synonyms: 2-(4-nitrophenoxy1)-1-(piperidin-1-yl)ethanone
• CAS NO: 50508-35-5
• Molecular Weight: 264.281
• Mol File: 50508-35-5.mol

Chemical Properties

• CAS DataBase Reference: 2-(4-nitrophenoxy1)-1-(piperidin-1-yl)ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-nitrophenoxy1)-1-(piperidin-1-yl)ethanone(50508-35-5)
• EPA Substance Registry System: 2-(4-nitrophenoxy1)-1-(piperidin-1-yl)ethanone(50508-35-5)

Safety Data

• Hazardous Substances Data: 50508-35-5(Hazardous Substances Data)

Usage

Chemical composition

Contains a nitrophenyl group and a piperidin-1-yl group attached to an ethanone molecule.

Physical form

Crystalline solid.

Uses

Primarily used as a building block in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds.

Reactivity

Known for its ability to react with other chemicals to form various derivatives, making it a versatile intermediate in the production of a wide range of organic compounds.

Handling precautions

Should be handled with care due to potential hazardous properties and used in a controlled laboratory setting by trained individuals.

Upstream product

• 110-89-4 piperidine 
• 20142-88-5 2-(4-nitrophenoxy)acetyl chloride 
• 1798-11-4 4-nitrophenoxyacetic acid 

Downstream Products

• 76870-14-9 2-(4-aminephenoxy)-1-(piperidin-1-yl)ethanone 
• 110506-67-7 2-(4-Isothiocyanato-phenoxy)-1-piperidin-1-yl-ethanone 

Relevant articles and documents

(E)-3-(Aryl(arylamino)methylene)indolin-2-one derivatives: An efficient synthetic approach and evaluation of their cancer inhibitory activity

A series of (E)-3-(aryl(arylamino)methylene)indolin-2-one derivatives were synthesised using an efficient synthetic approach. The method involved reaction of 3-bromo-3-(bromo(aryl)methyl)indolin-2-one with substituted anilines through nucleophilic substitution and a simultaneous elimination using NaHCO3 in DMF. The anticancer activity of the products against four cell lines, HCT-116, A549, SKOV3 and MDA-MB-231, was also evaluated, and several compounds showed moderate inhibitory activity.

Synthesis of Some New 3-Methoxy-4-acylaminophenylisothiocyanates, 4'-Isothiocyanatophenoxyacetamides/Isobutyramides as Possible Anthelmintic Agents

A number of new 3-methoxy-4-acylaminophenylisothiocyanates (II and III), 4'-isothiocyanatophenoxyacetamides (IV) and 4-isothiocyanatophenoxyisobutyramides (V) have been synthesized and tested for anthelmintic, antiamoebic and antitrichomonal activities.