505086-85-1

Upstream product

• 100-51-6 benzyl alcohol 
• 505086-84-0 5-(tert-butyl-dimethyl-silanyloxymethyl)-4-(1H-indol-3-yl)-2-oxo-pyrrolidine-3-carboxylic acid 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 120-72-9 indole 
• 505086-78-2 (R,R)-4-[(2,2-dimethyl-4,6-dioxo-1,3-dioxan-5-yl)-(1H-indol-3-yl)methyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylic acid tert-butyl ester 
• 505086-83-9 (3S,4R,5R)-5-(tertbutyldimethylsilanyloxymethyl)-4-(1H-indol-3-yl)-2-oxopyrrolidine-3-carboxylic acid methyl ester 
• 505086-82-8 (3S,4R,5R)-5-hydroxymethyl-4-(1H-indol-3-yl)-2-oxopyrrolidine-3-carboxylic acid methyl ester 
• 505086-79-3 (R,R)-4-[(2,2-dimethyl-4,6-dioxo[1,3]dioxan-5-yl)(1H-indol-3-yl)methyl]-2,2-dimethyl-1,3-oxazolidine-3-carboxylic acid benzyl ester 

Relevant academic research and scientific papers

Diastereocontrolled multicomponent pathway to 3,4-heterocycle-annulated tetrahydro-β-carbolines

A diastereoselective synthesis, using the Yonemitsu-type trimolecular condensation as the key step, has been used for the preparation of 3,4-heterocycle(furanone-, pyrrolidinone- and pyranone-) annulated tetrahydro-β-carbolines. The chirality of D-gly-cer

Synthesis of chiral 2′,3′-pyranone(pyrrolidinone)-fused tryptamines

Chiral pyrano- and pyrrolidino-fused tryptamines were prepared by a diasteroselective trimolecular condensation between indole, Garner's aldehyde and Meldrum's acid, followed by selective functional group transformations.