505087-28-5

Basic information

• Product Name: 2-(4-benzyloxy-phenyl)-8-methyl[1,2,4]triazolo[1,5-a]pyridine
• Synonyms: 2-(4-benzyloxy-phenyl)-8-methyl[1,2,4]triazolo[1,5-a]pyridine
• CAS NO: 505087-28-5
• Molecular Weight: 315.374
• Mol File: 505087-28-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(4-benzyloxy-phenyl)-8-methyl[1,2,4]triazolo[1,5-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-benzyloxy-phenyl)-8-methyl[1,2,4]triazolo[1,5-a]pyridine(505087-28-5)
• EPA Substance Registry System: 2-(4-benzyloxy-phenyl)-8-methyl[1,2,4]triazolo[1,5-a]pyridine(505087-28-5)

Safety Data

• Hazardous Substances Data: 505087-28-5(Hazardous Substances Data)

Upstream product

• 52805-36-4 4-benzyloxybenzonitrile 
• 55899-02-0 3-methyl-N-aminopyridinium mesitylenesulfonate 

Downstream Products

• 1308247-11-1 8-methyl-2-[4-(2-piperidin-1-ylethoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridine 
• 1308247-09-7 8-methyl-2-[4-(2-pyrrolidin-1-ylethoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridine 
• 1308247-12-2 8-methyl-2-[4-(2-morpholino-4-ylethoxy)phenyl]-[1,2,4]triazolo[1,5-a]pyridine 
• 898533-78-3 2-[4-(2-bromoethoxy)phenyl]-8-methyl[1,2,4]triazolo[1,5-a]pyridine 
• 898533-76-1 4-(8-methyl[1,2,4]triazolo[1,5-a]pyridin-2-yl)phenol 

Relevant articles and documents

Synthesis and antitumor activities of 2-(substituted)phenyl-1,2,4- triazolo[1,5-a]pyridines

(Chemical Equation Presented) Twenty-three 2-(substituted)phenyl-1,2,4- triazolo[1,5-a]pyridines have been synthesized by cyclo-additison reaction between N-amino methylpyridinium mesitylenesulfonates and substituted benzonitriles under the presence of po

Regioselection in 1,3-dipolar cycloadditions of 3-methylpyridine N-imide to aromatic carbonitriles. Synthesis of 2-aryl-8-methyl[1,2,4]triazolo [1,5-a]pyridines

1-Amino-3-methylpyridinium mesitylenesulfonate (3) reacts with aromatic nitriles in the presence of potassium hydroxide, undergoing 1,3-dipolar cycloaddition followed by elimination of H2 to give 2-aryl-8-methyl[1,2,4]triazolo[1,5-a]pyridines as the major products, rather than the 6-methyl isomers.