505097-46-1Relevant academic research and scientific papers
Synthesis of 2,3-dihydropyrrolizines from Weinreb 3-(pyrrolidin-2-ylidene)propionamides or Weinreb N-vinylprolinamides
Calvo, Luis,Gonzalez-Ortega, Alfonso,Sanudo, M. Carmen
, p. 2450 - 2456 (2002)
Weinreb 3-(pyrrolidin-2-ylidene)propionamides and Weinreb N-vinylprolinamides were used for the synthesis of 2,3-dihydropyrrolizines. The selective reaction of the carboxamide group with organometallic compounds allowed us to obtain a great variety of carbonyl intermediates, analogous to the Hantzsch and Knorr pyrrole synthesis, which were thermally cyclized.
