50518-88-2Relevant academic research and scientific papers
BENZOTELLUROPHENES SUBSTITUES EN POSITION 3
Talbot, J-M.,Piette, J-L.,Renson, M.
, p. 763 - 772 (2007/10/02)
3-substituted benzo(b)tellurophenes can be obtained through Wittig or Wittig-Horner reaction on 2H-benzo(b)tellurophene-3-one (telluroindoxyl).This reaction shows a partial isomerisation specific of the tellurium series, due to breaking of Te-CH2 bond.The products so obtained can lead to various mono 3-substituted derivatives (CH3, CHO, CH2OH, COOH, COOCH3, CN, CONH2).Reaction of triphenylphosphin/TeX4 on the same substrate leads to 3-chloro and 3-bromo benzo(b)tellurophenes, which could not be obtained by halogenation of the basic heterocycle.Acetylation of benzo(b)tellurophene with Ac2O/CF3COOH leads to a mixture 76/24 of 2-acetyl and 3-acetylbenzo(b)tellurophenes, which could be separated through thin-layer chromatography.
